{"id":"W2566967253","doi":"10.1093/neuonc/now212.040","title":"ACTR-42. CLINICAL TRIALS OF VAL-083 IN PATIENTS WITH CHEMORESISTANT GLIOBLASTOMA","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Bevacizumab; Medicine; Oncology; Clinical trial; Internal medicine; Phases of clinical research; Biomarker; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001955897,0.001565934,0.001589927,0.000736598,0.0005548621,0.001023275,0.0008037247,0.001737114,0.005683988],"category_scores_gemma":[0.0009252275,0.00057308,0.00128532,0.0006438454,0.0007954183,0.000715836,0.0004129418,0.003268442,0.001518857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008192433,"about_ca_system_score_gemma":0.001707349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515517,"about_ca_topic_score_gemma":0.004687352,"domain_scores_codex":[0.9992748,0.0004369769,0.00002860715,0.00008222389,0.00005607673,0.0001213764],"domain_scores_gemma":[0.9994749,0.00006031413,0.00007499768,0.00004186457,0.00004414794,0.0003037276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7602049,0.04095867,0.002424367,0.001270373,0.001233558,0.0003566627,0.0003413748,0.00204034,0.02357275,0.00102557,0.01215772,0.1544139],"study_design_scores_gemma":[0.6097693,0.3669769,0.008051119,0.0001075427,0.0002968294,0.0002395654,0.00007611835,0.0009857548,0.001995662,0.0007311255,0.01072368,0.0000464428],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9615688,0.01004571,0.0005917235,0.002470287,0.000653439,0.006716891,0.002615384,0.0005427087,0.01479506],"genre_scores_gemma":[0.9733691,0.004671498,0.001560307,0.003277874,0.0002901471,0.005959376,0.003271032,0.00005920318,0.007541458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005683988,"threshold_uncertainty_score":0.01901484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05183609190472253,"score_gpt":0.3780606727673279,"score_spread":0.3262245808626053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}