{"id":"W2567166227","doi":"10.1158/1538-7445.transcagen-a1-06","title":"Abstract A1-06: Recurrent mutations of hormone-positive breast cancer and association with outcome","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Breast cancer; Oncology; Massive parallel sequencing; Internal medicine; Exome; Exome sequencing; Medicine; Cancer; DNA sequencing; Biology; Genetics; Gene; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001196952,0.0004648241,0.0005139717,0.001053609,0.0004094125,0.0008664213,0.0005854049,0.0005360193,0.007545809],"category_scores_gemma":[0.002545706,0.0001644042,0.001381804,0.001709025,0.0002306263,0.0002464165,0.0003271589,0.0006342358,0.0008260722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003144236,"about_ca_system_score_gemma":0.0005456039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004994793,"about_ca_topic_score_gemma":0.004416015,"domain_scores_codex":[0.9995112,0.0001057314,0.00005214798,0.0001775726,0.000107199,0.00004603324],"domain_scores_gemma":[0.9975883,0.0009937533,0.0006508368,0.0001691058,0.0003095031,0.0002884586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002901524,0.00006465009,0.9774088,0.0006200105,0.002357434,0.0002328845,0.00008750828,0.0003211524,0.003892721,0.00006422705,0.002302793,0.009746297],"study_design_scores_gemma":[0.00007476917,0.0002743945,0.9932352,0.00008522253,0.002790992,0.0004731475,0.00008774786,0.0007694646,0.0008464606,0.0001345676,0.001217069,0.0000110978],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828073,0.004209236,0.0005680681,0.00028137,0.00004027559,0.00002142732,0.01093377,0.00005539705,0.001083154],"genre_scores_gemma":[0.9935806,0.0005930572,0.0003679538,0.00006882934,0.00004512406,0.00002613793,0.004437735,0.00002228243,0.0008584215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007545809,"threshold_uncertainty_score":0.02524322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04976387151254262,"score_gpt":0.3836792949690945,"score_spread":0.3339154234565519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}