{"id":"W2567194800","doi":"10.4049/jimmunol.196.supp.76.11","title":"Naturally-derived bacterial nano-particles engage diverse innate receptors, driving the activation of dendritic cells and leading to the establishment of potent adaptive immune responses.","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"CD80; CD86; Biology; Inflammasome; Cell biology; Immune system; Dendritic cell; Antigen; Acquired immune system; Antigen-presenting cell; T cell; Antigen presentation; Innate immune system; CD40; Microbiology; Immunology; Cytotoxic T cell; In vitro; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001834378,0.0003564542,0.0002438138,0.0001737029,0.0001278238,0.0003796202,0.0001232115,0.0003963745,0.001173936],"category_scores_gemma":[0.0001336995,0.0001187318,0.000418427,0.0000957548,0.000198703,0.0002710747,0.0003352207,0.0005119826,0.0005352614],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003090703,"about_ca_system_score_gemma":0.0001903861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001335878,"about_ca_topic_score_gemma":0.0001578284,"domain_scores_codex":[0.9998197,0.00003006489,0.00001716788,0.00003390851,0.00005903359,0.00004024178],"domain_scores_gemma":[0.9999048,0.00001935186,0.0000264502,0.00001175793,0.00002158181,0.00001612495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005747173,0.00003974134,0.000487892,0.0001324265,0.000007998934,0.00005043996,0.00001341917,0.00007743741,0.9954149,0.0003178748,0.00007786135,0.00332259],"study_design_scores_gemma":[0.000017068,0.0004087229,0.001924765,0.00003164438,0.00001482243,0.0002505905,0.00004382088,0.0007458917,0.9916036,0.0003055155,0.004647715,0.00000592656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9577593,0.008482695,0.02698084,0.0003080888,0.0002957503,0.0002334781,0.0004575416,0.0001606947,0.005321648],"genre_scores_gemma":[0.9874742,0.001921941,0.007714597,0.0002010395,0.00004613936,0.0001144759,0.000281565,0.00001736564,0.002228654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173936,"threshold_uncertainty_score":0.003927231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01551992818841711,"score_gpt":0.2316106125939294,"score_spread":0.2160906844055123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}