{"id":"W2567289032","doi":"10.1158/1538-7445.am2015-2260","title":"Abstract 2260: Defining molecular mechanisms linking Endophilin A2 to metastasis in human breast cancer models","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Invadopodia; Cancer research; Metastasis; Breast cancer; Internalization; Triple-negative breast cancer; Cancer; Estrogen receptor; Epithelial–mesenchymal transition; Extracellular matrix; Biology; Pathology; Medicine; Receptor; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958012,0.0004005803,0.0002190478,0.0003917661,0.0001734659,0.000276728,0.000234602,0.0002758929,0.001757599],"category_scores_gemma":[0.00007419062,0.0001397912,0.0002872843,0.0001586606,0.0001717586,0.0001971739,0.000176345,0.0004593805,0.0005631864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003385354,"about_ca_system_score_gemma":0.0002283662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008613397,"about_ca_topic_score_gemma":0.0009525796,"domain_scores_codex":[0.999896,0.00002432473,0.000007577566,0.00001845417,0.00003097964,0.00002248881],"domain_scores_gemma":[0.9999517,0.000007730207,0.000009979951,0.000006612696,0.000007076616,0.00001687961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001844337,0.0000887272,0.0001680174,0.00003899248,0.000005595701,0.00005219984,0.000006703759,0.0001196491,0.998018,0.0002537387,0.00009755088,0.0009663877],"study_design_scores_gemma":[0.00006448683,0.001226687,0.007814062,0.00001081724,0.00002705724,0.0004871848,0.00002696947,0.003775979,0.9814819,0.0001846017,0.004892593,0.000007659143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824728,0.002549485,0.008411821,0.0002294415,0.00005699753,0.000226253,0.001658938,0.0001175345,0.004276626],"genre_scores_gemma":[0.9810296,0.0017147,0.006412089,0.0001323601,0.00002749763,0.0002995341,0.00260189,0.00002916074,0.007753239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001757599,"threshold_uncertainty_score":0.00587976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236704041065268,"score_gpt":0.4131851372704798,"score_spread":0.2895147331639531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}