{"id":"W2567319477","doi":"10.1002/jcp.25751","title":"Super‐resolution structure of DNA significantly differs in buccal cells of controls and Alzheimer's patients","year":2016,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba; Queen's University","funders":"Canada Foundation for Innovation","keywords":"Buccal administration; DNA; Buccal swab; Cell nucleus; Biology; Nucleus; Nuclear DNA; Resolution (logic); Alzheimer's disease; Cell biology; Molecular biology; Biophysics; Pathology; Disease; Medicine; Genetics; Gene; Mitochondrial DNA; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008455548,0.0001212705,0.0003493318,0.00007866752,0.00001177721,0.000001449531,0.0001543884,0.0001739173,0.000008706469],"category_scores_gemma":[0.0000608495,0.00008223934,0.00008179517,0.0000423607,0.0002635578,0.000009302764,0.00005577261,0.00009240413,1.41832e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001185,"about_ca_system_score_gemma":0.00003866127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004064565,"about_ca_topic_score_gemma":0.000002351236,"domain_scores_codex":[0.9990292,0.0001135788,0.0004505134,0.0001515454,0.00009268146,0.0001624848],"domain_scores_gemma":[0.9991751,0.00003560437,0.0004238526,0.0001489245,0.0001703203,0.00004624642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004893515,0.00008132762,0.003440343,0.00001461308,0.00005270597,0.000001377658,0.00002500941,0.00001239588,0.9950897,0.00001862465,0.00004769175,0.0007268605],"study_design_scores_gemma":[0.001231706,0.001073594,0.01349141,0.00004573962,0.00002595604,0.000002946946,0.00001770214,0.000006030647,0.9834368,0.000495731,0.00008896941,0.00008345934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994588,0.0006632865,0.004483233,0.00001978309,0.00008032608,0.0001174189,0.00004286118,0.000001390713,0.000003751867],"genre_scores_gemma":[0.9977177,0.0002591766,0.00192532,0.0000198364,0.00005448448,7.659342e-7,0.000008372182,0.00001147703,0.000002813743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01165295,"threshold_uncertainty_score":0.3353623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004584951234732594,"score_gpt":0.2223920257949979,"score_spread":0.2178070745602653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}