{"id":"W2567591334","doi":"10.1111/bioe.12309","title":"Human Nuclear Genome Transfer (So‐Called Mitochondrial Replacement): Clearing the Underbrush","year":2016,"lang":"en","type":"review","venue":"Bioethics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Clearing; Mitochondrial DNA; Genome; Business; Biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01320788,0.000548364,0.001060969,0.00108267,0.004232287,0.007279574,0.002054282,0.01194499,0.003612984],"category_scores_gemma":[0.01496166,0.0003186539,0.0007364962,0.0006589876,0.05634835,0.01677982,0.006925839,0.01346741,0.001618161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003326076,"about_ca_system_score_gemma":0.003869341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001607125,"about_ca_topic_score_gemma":0.001975591,"domain_scores_codex":[0.9916549,0.00419563,0.0004297253,0.001009491,0.002128304,0.0005818969],"domain_scores_gemma":[0.9908422,0.006676293,0.0007034312,0.0007219472,0.0007447225,0.0003114041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002197618,0.00001007792,0.0001205666,0.0001789626,0.000008233535,0.0001368184,0.002963005,0.00007914811,0.0002154154,0.9546996,0.02199434,0.01957189],"study_design_scores_gemma":[0.000008121782,0.00004430338,0.000173795,0.0007086593,0.00001158453,0.0005026657,0.002405083,0.000131366,0.0004222802,0.4151128,0.5804518,0.00002739074],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.005873531,0.2131426,0.02302743,0.6504942,0.02092991,0.00002532088,0.00003449951,0.0001111348,0.08636145],"genre_scores_gemma":[0.278505,0.1540098,0.01133462,0.4830753,0.02598,0.0002099492,0.00005790261,0.0004148685,0.04641255],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01320788,"threshold_uncertainty_score":0.0698508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08021693006599553,"score_gpt":0.3487659899122099,"score_spread":0.2685490598462144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}