{"id":"W2568226435","doi":"10.1128/iai.00905-16","title":"MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis","year":2017,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Cathelicidin; Mucin; Entamoeba histolytica; Mucin 2; Biology; Goblet cell; Mucus; Antimicrobial peptides; Colitis; Microbiology; Biochemistry; Immunology; Antimicrobial; Gene expression; Epithelium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001911198,0.0004793541,0.0004205596,0.0002773601,0.0001482983,0.0003671243,0.0001103209,0.000386541,0.001090087],"category_scores_gemma":[0.0001519755,0.0002810227,0.000428832,0.0001513441,0.0003175285,0.0002652364,0.0002716841,0.0007949595,0.0002486375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003986674,"about_ca_system_score_gemma":0.0002182845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006636354,"about_ca_topic_score_gemma":0.0007188689,"domain_scores_codex":[0.9997113,0.00005893859,0.00002715516,0.00004837396,0.00005477934,0.00009934507],"domain_scores_gemma":[0.9997265,0.00002082753,0.00007192892,0.000031985,0.00002695427,0.0001217412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002203597,0.000008731678,0.0001305607,0.0000170962,0.000001890837,0.00002008842,0.000006240659,0.00000777965,0.9994422,0.000009230205,0.000005919631,0.0001298962],"study_design_scores_gemma":[0.00004196794,0.0005677509,0.02059433,0.00001609144,0.00002324334,0.0001996173,0.00007510617,0.0006733855,0.9765176,0.00004238456,0.001242337,0.000006152322],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963127,0.001897157,0.0008306695,0.00009909283,0.00003385188,0.00002889756,0.0003127677,0.00003291725,0.0004519915],"genre_scores_gemma":[0.9958168,0.0006393278,0.001138197,0.00008802074,0.00001294949,0.00005743832,0.0003457649,0.0000178342,0.001883705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001090087,"threshold_uncertainty_score":0.003646672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01797440403691857,"score_gpt":0.2782741439714305,"score_spread":0.2602997399345119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}