{"id":"W2568716025","doi":"10.1182/blood.v126.23.3465.3465","title":"Murine Bone Marrow-Derived Megakaryocytes Are Capable of Antigen Cross-Presentation on Major Histocompatibility Class (MHC) I Molecules","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"MHC class I; Antigen presentation; Cross-presentation; Biology; Major histocompatibility complex; Antigen processing; Cytotoxic T cell; CD8; Antigen; MHC restriction; Antigen-presenting cell; Cell biology; Molecular biology; T cell; Immunology; Immune system; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001499517,0.0003849598,0.0002397952,0.0001518466,0.00009870548,0.0002240207,0.000169678,0.0003104539,0.000825547],"category_scores_gemma":[0.00007597899,0.0001956042,0.0002211491,0.00008963514,0.00008725918,0.0001378137,0.0002170453,0.000510792,0.0005420997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001717035,"about_ca_system_score_gemma":0.00005997588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002101921,"about_ca_topic_score_gemma":0.0003557437,"domain_scores_codex":[0.9998655,0.0000236433,0.00001533437,0.00002823565,0.00003336995,0.00003378276],"domain_scores_gemma":[0.9999222,0.00001877594,0.00001936046,0.00001252263,0.00001005827,0.00001716938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000411049,0.00001223814,0.0001188845,0.00002146342,0.000002990002,0.00003497325,0.000006412136,0.00002628652,0.9993511,0.00006032501,0.00001337437,0.0003108405],"study_design_scores_gemma":[0.00002922946,0.0002385042,0.007119907,0.000009585895,0.00002168649,0.000299669,0.00001376994,0.0009426657,0.9888333,0.00005161656,0.002436468,0.000003573045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902133,0.002620225,0.005038957,0.00007891972,0.00003344458,0.00005077236,0.000548846,0.00006818355,0.001347293],"genre_scores_gemma":[0.9901169,0.001163224,0.004793759,0.00007966486,0.00001227047,0.00006436843,0.00120721,0.00002845239,0.00253412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000825547,"threshold_uncertainty_score":0.002761781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0283926450475033,"score_gpt":0.2924842514839224,"score_spread":0.2640916064364192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}