{"id":"W2568716921","doi":"10.1182/blood.v120.21.3016.3016","title":"Discovering Optimal Targets for Adoptive T-Cell Immunotherapy of Leukemia.","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Antigen; Immunology; Adoptive cell transfer; Immunotherapy; CD8; Transplantation; CTL*; Leukemia; Cancer research; Cancer immunotherapy; Minor histocompatibility antigen; Biology; T cell; Major histocompatibility complex; Immune system; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002615063,0.0003425982,0.0002976249,0.0003807723,0.0001023905,0.0004437165,0.0002116691,0.0003740781,0.001150703],"category_scores_gemma":[0.0001550616,0.0001470116,0.0002140508,0.0002611672,0.0001153959,0.0004530773,0.000195107,0.000525763,0.0007204002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002288791,"about_ca_system_score_gemma":0.0001704328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001266267,"about_ca_topic_score_gemma":0.0002929463,"domain_scores_codex":[0.99989,0.00002352387,0.000008037952,0.00001806909,0.00003452331,0.00002590855],"domain_scores_gemma":[0.9999398,0.00001204079,0.00001950396,0.000004444292,0.00001191251,0.00001227578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001251085,0.00007152945,0.0003781556,0.0001203443,0.000006832509,0.00002991621,0.00001173939,0.0005446819,0.9832011,0.00028395,0.0001888867,0.01503786],"study_design_scores_gemma":[0.000111383,0.001973819,0.002945841,0.00004282378,0.00006589502,0.0002649435,0.00007023913,0.004885255,0.9720987,0.0008454293,0.01668462,0.00001096243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.918214,0.03729837,0.03664107,0.0009201919,0.0001373982,0.0004672004,0.001133531,0.0003179513,0.004870267],"genre_scores_gemma":[0.9456906,0.01184025,0.03719975,0.0003433388,0.00006543713,0.0002864594,0.001423492,0.00005199792,0.00309877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001150703,"threshold_uncertainty_score":0.003849447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02272813141061957,"score_gpt":0.2976592045055155,"score_spread":0.2749310730948959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}