{"id":"W2568859315","doi":"10.1021/acs.biochem.6b01263","title":"Self-Assembly of Human Profilin-1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Oligomer; Nuclear magnetic resonance spectroscopy; Monomer; Profilin; Chemistry; Actin; Relaxation (psychology); Biophysics; Conformational isomerism; Spectroscopy; Nuclear magnetic resonance; Crystallography; Polymer; Cytoskeleton; Biochemistry; Stereochemistry; Molecule; Biology; Cell; Actin cytoskeleton; Polymer chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002276358,0.0002297931,0.0001445755,0.0003333188,0.000173142,0.0002018429,0.0001740471,0.0003120218,0.0004725473],"category_scores_gemma":[0.0003631423,0.0001396268,0.0001166411,0.000187658,0.0001760223,0.0002341863,0.000137329,0.0003331006,0.0001668366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002322641,"about_ca_system_score_gemma":0.00009024863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007496829,"about_ca_topic_score_gemma":0.0007381338,"domain_scores_codex":[0.9998567,0.00003279822,0.000007541237,0.00004023069,0.00004167899,0.00002100233],"domain_scores_gemma":[0.999785,0.00007080231,0.00005333731,0.0000161999,0.0000289839,0.00004566832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001661716,0.000007454857,0.0001391058,0.000008220733,0.000002204623,0.0000185161,0.00002276846,0.00003655584,0.9993914,0.00002622816,0.00001039755,0.0003205138],"study_design_scores_gemma":[0.000008891121,0.0001701837,0.01115254,0.000006563326,0.00001125658,0.0002033664,0.00004244403,0.004315898,0.9833165,0.00006026711,0.0007020033,0.00001019446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952666,0.0009805574,0.002905377,0.00004790516,0.00000546773,0.00001714804,0.00009506267,0.00003193315,0.0006499971],"genre_scores_gemma":[0.9915,0.0006500093,0.006301274,0.00007509779,0.000008652481,0.00002899591,0.000403521,0.00001370492,0.001018817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007496829,"threshold_uncertainty_score":0.001685202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005712955387688838,"score_gpt":0.242782476501957,"score_spread":0.2370695211142682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}