{"id":"W2568859315","doi":"10.1021/acs.biochem.6b01263","title":"Self-Assembly of Human Profilin-1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Oligomer; Nuclear magnetic resonance spectroscopy; Monomer; Profilin; Chemistry; Actin; Relaxation (psychology); Biophysics; Conformational isomerism; Spectroscopy; Nuclear magnetic resonance; Crystallography; Polymer; Cytoskeleton; Biochemistry; Stereochemistry; Molecule; Biology; Cell; Actin cytoskeleton; Polymer chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001061944,0.000264858,0.0002289018,0.00002304493,0.0003769699,0.00007844329,0.0006643722,0.0003122019,0.0001207301],"category_scores_gemma":[0.00008417339,0.0002877768,0.0001734832,0.00004091728,0.0001108104,0.000007451948,0.0002588099,0.0001911361,0.00001884764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004112239,"about_ca_system_score_gemma":0.00007472412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006598089,"about_ca_topic_score_gemma":0.00001086132,"domain_scores_codex":[0.9985375,0.00002449597,0.0003274245,0.0005743349,0.0001873763,0.0003488542],"domain_scores_gemma":[0.9981135,0.000005418115,0.0002934255,0.001305279,0.0001459885,0.0001363498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004765028,0.0001524243,0.0001992618,0.00007186508,0.00003045155,0.000003939996,0.00001707161,9.799085e-8,0.9926704,0.00004246428,0.00646506,0.0002993852],"study_design_scores_gemma":[0.0005272243,0.000356993,0.0002229332,0.0000366329,0.00003515437,0.0000155179,0.00004692321,0.0001197013,0.9514406,0.00002085887,0.04688039,0.0002970439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886138,0.002790796,0.00003474841,0.00008207103,0.0001508087,0.0001890326,0.000125657,0.00003711712,0.007975912],"genre_scores_gemma":[0.9941311,0.0003676527,0.001006095,0.00004487024,0.0002556513,0.00001938018,0.0001688149,0.00005816424,0.003948237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0412297,"threshold_uncertainty_score":0.9999574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005712955387688838,"score_gpt":0.242782476501957,"score_spread":0.2370695211142682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}