{"id":"W2569806458","doi":"10.18632/oncotarget.14496","title":"Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells","year":2017,"lang":"en","type":"article","venue":"Oncotarget","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"TRPM7; Protein kinase B; PI3K/AKT/mTOR pathway; Viability assay; MAPK/ERK pathway; Cancer research; Matrigel; U87; Cell migration; Cell culture; Activator (genetics); Medicine; Biology; Glioma; Cell biology; Signal transduction; Internal medicine; Angiogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008444498,0.0002374473,0.0002382812,0.0001550087,0.000152889,0.0002090132,0.000148498,0.000206966,0.001401082],"category_scores_gemma":[0.00006509387,0.00006908934,0.0003538179,0.0001395937,0.0001402542,0.0002159418,0.0001687914,0.0005602759,0.0004083087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000195314,"about_ca_system_score_gemma":0.000258889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00151835,"about_ca_topic_score_gemma":0.002361286,"domain_scores_codex":[0.9999002,0.00001287236,0.00001160866,0.00001153246,0.00002853767,0.0000352684],"domain_scores_gemma":[0.9999642,0.000006437081,0.000006335264,0.00000410753,0.000008831449,0.00001009168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002470611,0.00006659474,0.000237273,0.00007921582,0.00000671101,0.0000719242,0.00003344601,0.00006064029,0.9959031,0.00004431049,0.0001752634,0.003074372],"study_design_scores_gemma":[0.00003860405,0.001045079,0.01098537,0.00001899472,0.00002984171,0.0001777531,0.0001928778,0.001758786,0.9840364,0.00005175383,0.001657166,0.000007423352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941478,0.001928639,0.001086704,0.0002518641,0.00005948703,0.00002739026,0.0002658133,0.00006643547,0.002165768],"genre_scores_gemma":[0.9950222,0.001426184,0.001164085,0.0001413215,0.00001099824,0.00004797966,0.0003153861,0.00001158252,0.001860259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00151835,"threshold_uncertainty_score":0.00468713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01192057506740419,"score_gpt":0.2805971857816431,"score_spread":0.2686766107142389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}