{"id":"W2570093446","doi":"10.1093/hmg/ddx001","title":"Cyclodextrin has conflicting actions on autophagy flux <i>in vivo</i> in brains of normal and Alzheimer model mice","year":2017,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; Alzheimer's Association; National Institute of Neurological Disorders and Stroke; National Institute on Aging; University of Alberta","keywords":"Autophagy; Lysosome; Biology; Autophagosome; Cathepsin B; Cell biology; Cathepsin D; Sequestosome 1; Neurodegeneration; Proteostasis; Cathepsin; Tauopathy; Amyloid precursor protein; Population; Biochemistry; Alzheimer's disease; Internal medicine; Medicine; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":{"n_in":0,"stratum":"fund_new","weight":1678.9,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Cyclodextrin effects on autophagy in mouse brains; preclinical neuroscience."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"The work studies autophagy and cyclodextrin effects in disease models, not research itself."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Biomedical study of cyclodextrin effects on autophagy in AD mice; domain neuroscience."}}}