{"id":"W2570200366","doi":"10.1182/blood.v126.23.1542.1542","title":"Lymphoma Symptoms: Data from a Phase 3, International, Randomized, Open-Label, Multicenter Study in Patients with Previously Treated Mantle Cell Lymphoma (MCL) Treated with Ibrutinib Vs. Temsirolimus","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Mantle cell lymphoma; Medicine; Internal medicine; Ibrutinib; Temsirolimus; Clinical endpoint; Lymphoma; Phases of clinical research; International Prognostic Index; Oncology; Randomized controlled trial; Gastroenterology; Clinical trial; Rituximab; Leukemia; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00513302,0.001310156,0.002434863,0.0004488948,0.0005792695,0.001157941,0.001272505,0.001509827,0.004379308],"category_scores_gemma":[0.002130642,0.0006102688,0.002947589,0.0007530966,0.001293975,0.001318409,0.0005596341,0.002414637,0.0007436075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008663665,"about_ca_system_score_gemma":0.001442839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007230655,"about_ca_topic_score_gemma":0.001875989,"domain_scores_codex":[0.9980082,0.001297837,0.0001580188,0.0002105734,0.0001299331,0.0001955384],"domain_scores_gemma":[0.9971671,0.0006006957,0.0008365566,0.0001859854,0.0001631241,0.001046616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9506761,0.01324811,0.008210629,0.0007693377,0.003046565,0.00005805681,0.0001069124,0.0003713686,0.005470141,0.00007379727,0.0009763194,0.01699269],"study_design_scores_gemma":[0.8034549,0.1683661,0.02365956,0.00004899827,0.002360008,0.00008523264,0.00006456691,0.0003049456,0.0006159664,0.00009267731,0.0009167773,0.00003015223],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895694,0.005144127,0.0003821113,0.0004592469,0.0001439995,0.001943288,0.001334737,0.00004763352,0.0009754098],"genre_scores_gemma":[0.9909467,0.001644033,0.000956805,0.0009476689,0.0002837487,0.002507695,0.001987869,0.00001464545,0.0007109622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00513302,"threshold_uncertainty_score":0.02714634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0463762389773181,"score_gpt":0.3297237700807319,"score_spread":0.2833475311034138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}