{"id":"W2570246089","doi":"10.14283/jpad.2015.66","title":"POST HOC EVIDENCE FOR AN ADDITIVE EFFECT OF MEMANTINE AND DONEPEZIL: CONSISTENT FINDINGS FROM DOMINO-AD STUDY AND MEMANTINE CLINICAL TRIAL PROGRAM","year":2015,"lang":"en","type":"article","venue":"The Journal of Prevention of Alzheimer s Disease","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hendrix Genetics (Canada)","funders":"","keywords":"Memantine; Donepezil; Medicine; Randomized controlled trial; Clinical trial; Post-hoc analysis; Placebo; Internal medicine; Dementia; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005925431,0.000156959,0.0006561313,0.0001278443,0.00005453671,0.00002411457,0.0001262425,0.00004220026,0.00004744603],"category_scores_gemma":[0.001945906,0.00009391443,0.0002680873,0.00009271484,0.0003230392,0.0002603734,0.0001013447,0.0001766208,7.567408e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008232273,"about_ca_system_score_gemma":0.0002406205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001650551,"about_ca_topic_score_gemma":0.000005960447,"domain_scores_codex":[0.9969093,0.001127715,0.0009528736,0.0001917191,0.0006567396,0.0001616531],"domain_scores_gemma":[0.9966373,0.001072924,0.0006913944,0.0002022372,0.0009292475,0.0004669268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7340434,0.008353751,0.107138,0.0002232505,0.004476795,0.00004928003,0.0009641478,3.337081e-7,0.001848446,0.000005638732,0.0004036571,0.1424933],"study_design_scores_gemma":[0.1391962,0.1324067,0.7009825,0.001084853,0.02013477,0.00002776452,0.001572556,0.0001122469,0.004120823,0.0001739224,0.00005108853,0.0001366159],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989462,0.005817065,0.00005125466,0.0004355477,0.0001264092,0.004033762,0.00005873303,0.000006368451,0.000008862464],"genre_scores_gemma":[0.9989401,0.0004043847,0.000367974,0.00002929296,0.0001522944,0.00004799799,0.00001769672,0.00001348953,0.00002674155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5948471,"threshold_uncertainty_score":0.3829719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1770983267009565,"score_gpt":0.4866636798523904,"score_spread":0.3095653531514339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}