{"id":"W2570729870","doi":"10.1002/cncr.30496","title":"Confirmation of ProMisE: A simple, genomics‐based clinical classifier for endometrial cancer","year":2017,"lang":"en","type":"article","venue":"Cancer","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":960,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; McGill University Health Centre; McGill University; University Health Network; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; BC Cancer Foundation","keywords":"Medicine; Oncology; Endometrial cancer; DNA mismatch repair; Internal medicine; Lynch syndrome; Cancer; Bioinformatics; Colorectal cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005239184,0.0005008423,0.0005845624,0.001681057,0.000335205,0.0009273925,0.0006874249,0.0006079337,0.001384106],"category_scores_gemma":[0.009033511,0.0001352795,0.0004558119,0.0005096879,0.0003212255,0.0006053281,0.0006649405,0.0006879449,0.0007122135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004919689,"about_ca_system_score_gemma":0.0007519101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009586749,"about_ca_topic_score_gemma":0.001487701,"domain_scores_codex":[0.9987287,0.0004242457,0.0001349909,0.0002522535,0.0003468664,0.0001129578],"domain_scores_gemma":[0.995246,0.002488148,0.0005848018,0.0003193116,0.001103003,0.0002587663],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001302516,0.0001746826,0.8663648,0.0001055208,0.0001525637,0.0002272508,0.0001365265,0.003286633,0.01006013,0.0004472212,0.002960213,0.114782],"study_design_scores_gemma":[0.0005057047,0.003371161,0.7354598,0.000131682,0.0007535467,0.003424665,0.0005919854,0.2114705,0.02946326,0.004591278,0.01013229,0.0001041707],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799811,0.000477661,0.01436877,0.0007077859,0.00005607029,0.0001771883,0.001566271,0.000236187,0.002428982],"genre_scores_gemma":[0.9862006,0.00006825936,0.01161581,0.0001292083,0.00006085651,0.00006366527,0.001581918,0.00001549225,0.0002640465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005239184,"threshold_uncertainty_score":0.02770782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2019117188372056,"score_gpt":0.4746124613832805,"score_spread":0.2727007425460749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}