{"id":"W2570729870","doi":"10.1002/cncr.30496","title":"Confirmation of ProMisE: A simple, genomics‐based clinical classifier for endometrial cancer","year":2017,"lang":"en","type":"article","venue":"Cancer","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":960,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; McGill University Health Centre; McGill University; University Health Network; University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; BC Cancer Foundation","keywords":"Medicine; Oncology; Endometrial cancer; DNA mismatch repair; Internal medicine; Lynch syndrome; Cancer; Bioinformatics; Colorectal cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003110144,0.0001524675,0.0006150921,0.000105373,0.0001440037,0.0000286093,0.000174857,0.0001528794,0.0009869318],"category_scores_gemma":[0.0008722395,0.0001182623,0.0003204994,0.000113496,0.000173625,0.00008225009,0.00003236983,0.0001232406,0.000007265476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000242392,"about_ca_system_score_gemma":0.0007545681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000595618,"about_ca_topic_score_gemma":0.00013924,"domain_scores_codex":[0.9986535,0.00003269333,0.0005448616,0.0002994965,0.000224726,0.0002446777],"domain_scores_gemma":[0.9982287,0.0002985018,0.0005145816,0.0004739499,0.0002994383,0.0001848473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.02302646,0.0008663243,0.3594537,0.0009692908,0.001287104,0.00001152739,0.00009516102,0.00003940878,0.01037625,0.0005197123,0.01252612,0.590829],"study_design_scores_gemma":[0.1032218,0.002147503,0.4328237,0.0003969128,0.001691591,0.000002113419,0.00003297901,0.001831987,0.06873234,0.0006993792,0.387955,0.0004646924],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804248,0.00247647,0.001181221,0.0039851,0.003189954,0.003332874,0.0009819985,0.00005018434,0.00437737],"genre_scores_gemma":[0.9943618,0.0005744856,0.0006216263,0.0007341874,0.001834398,0.0008397452,0.00005491295,0.0000291409,0.0009496878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5903643,"threshold_uncertainty_score":0.9999263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2019117188372056,"score_gpt":0.4746124613832805,"score_spread":0.2727007425460749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}