{"id":"W2571432015","doi":"10.1182/blood.v108.11.721.721","title":"High Efficiency Clinical Scale Selective Depletion of Alloreacting T Cells Using Expanded T Lymphocytes as Antigen-Presenting Cells and a TH9402-Based Photodepletion Technique in HLA-Mismatched and Matched Donor-Recipient Pairs.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Leukapheresis; IL-2 receptor; Flow cytometry; Immunology; Peripheral blood mononuclear cell; Antigen; Lymphocyte; Molecular biology; Chemistry; Biology; T cell; Stem cell; In vitro; Biochemistry; Cell biology; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006666029,0.0003191561,0.0002974031,0.0001450652,0.0001621053,0.0002341653,0.0002828238,0.0002887928,0.001132012],"category_scores_gemma":[0.0001901746,0.0001321932,0.0001986335,0.0001026516,0.0002254965,0.000151086,0.0002872246,0.0005539414,0.0004608721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001225504,"about_ca_system_score_gemma":0.000203844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001354128,"about_ca_topic_score_gemma":0.0001983205,"domain_scores_codex":[0.9997078,0.0001019917,0.00001534801,0.00005840286,0.00007528455,0.00004118362],"domain_scores_gemma":[0.9999408,0.00001306687,0.00001069172,0.00001465901,0.000005333664,0.00001537582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001882777,0.001728463,0.001103598,0.0001002235,0.00002264612,0.0002182429,0.00005470475,0.0002451045,0.9707675,0.0001324631,0.0004138764,0.02333029],"study_design_scores_gemma":[0.001292123,0.04327637,0.01489678,0.00002308358,0.0001218312,0.003667728,0.0000691872,0.002289004,0.924793,0.0001414116,0.009415478,0.00001397281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788097,0.001581724,0.01626027,0.0001021909,0.0000608806,0.0009207599,0.0002649021,0.000200682,0.001798865],"genre_scores_gemma":[0.9915326,0.0005307941,0.005584633,0.00008453313,0.00002458961,0.0004089937,0.0004345373,0.00002201659,0.001377214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001132012,"threshold_uncertainty_score":0.003786981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374397635391449,"score_gpt":0.2879793427163764,"score_spread":0.2742353663624619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}