{"id":"W2571859589","doi":"10.1038/srep40539","title":"Aryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University Health Centre; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Aryl hydrocarbon receptor; microRNA; Transcription factor; Oxidative stress; Cancer research; Regulation of gene expression; CYP1B1; Biology; Inflammation; Chemistry; Immunology; Endocrinology; Gene; Cytochrome P450; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358901,0.0001567541,0.0001605504,0.0001812613,0.0001080412,0.0002039813,0.00007694208,0.0001572318,0.001482914],"category_scores_gemma":[0.000158666,0.0001206382,0.0001978426,0.0001142043,0.0002031506,0.0001056655,0.0002384276,0.0003213103,0.0003148868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001149765,"about_ca_system_score_gemma":0.0001281407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003704159,"about_ca_topic_score_gemma":0.0004763924,"domain_scores_codex":[0.9998453,0.00002521138,0.00001448356,0.00003468526,0.00004788551,0.00003234125],"domain_scores_gemma":[0.9998659,0.00002039122,0.00004253812,0.00001264648,0.00002709913,0.00003144675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001859869,0.00001979009,0.00225439,0.0000204203,0.000005967447,0.00003174467,0.00001422523,0.00001354061,0.9964119,0.00003617033,0.00003449584,0.0009714487],"study_design_scores_gemma":[0.00002724622,0.0005090296,0.2288011,0.00001313018,0.00004199074,0.0004831982,0.0001266937,0.0008195899,0.7664852,0.0001566313,0.002527126,0.000009009442],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995359,0.001614275,0.001555915,0.00008285075,0.00003034544,0.00001503343,0.000382047,0.00003500128,0.0009253654],"genre_scores_gemma":[0.9956447,0.0006556968,0.0007598039,0.00005367223,0.00001105583,0.00003063622,0.0003068984,0.00001129397,0.002526376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001482914,"threshold_uncertainty_score":0.004960835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01009944713544959,"score_gpt":0.2283353321282325,"score_spread":0.2182358849927829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}