{"id":"W2572266215","doi":"10.1016/j.gene.2017.01.018","title":"The p53 protein induces stable miRNAs that have the potential to modify subsequent p53 responses","year":2017,"lang":"en","type":"article","venue":"Gene","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University; Ottawa Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Carleton University","keywords":"Biology; microRNA; Mdm2; Messenger RNA; Molecular biology; Downregulation and upregulation; Suppressor; Microarray; Transcription (linguistics); Cell biology; Gene expression; Cancer research; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002021844,0.0003323292,0.0002436572,0.0002106196,0.0001242782,0.00028646,0.0001264524,0.0002929558,0.00101462],"category_scores_gemma":[0.0003459842,0.0001819629,0.000345267,0.0001300231,0.000234502,0.0002358348,0.000209975,0.0005854841,0.000527532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001984478,"about_ca_system_score_gemma":0.0001448802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001471314,"about_ca_topic_score_gemma":0.000184812,"domain_scores_codex":[0.9998405,0.00002347085,0.00001341538,0.00004987151,0.00003619286,0.00003641565],"domain_scores_gemma":[0.9997788,0.00006754036,0.00006045037,0.00003774513,0.0000277974,0.00002768248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005018235,0.000009188506,0.0001295539,0.00001378622,0.00000215281,0.00002973472,0.000007710397,0.00002432223,0.9989066,0.00005097518,0.000009192177,0.0007665955],"study_design_scores_gemma":[0.000003488457,0.0001915325,0.002843478,0.000002444648,0.000005496661,0.0001069684,0.00001042057,0.0003096505,0.9955338,0.00005994084,0.0009304667,0.000002362921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869673,0.002197776,0.008879757,0.00008804988,0.00005468877,0.00004886419,0.0002443606,0.0001664414,0.001352809],"genre_scores_gemma":[0.9939535,0.0007582355,0.003345942,0.00004716429,0.0000157794,0.00005308673,0.0003107089,0.00003186254,0.001483758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00101462,"threshold_uncertainty_score":0.003394246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02472923142953076,"score_gpt":0.2777531385274049,"score_spread":0.2530239070978741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}