{"id":"W2572477394","doi":"10.1182/blood.v114.22.1434.1434","title":"A Potent Stimulator of Self-Renewal in Combination with MEIS1 Overexpression Allows the Transformation of Late Committed Myeloid Progenitors.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Progenitor cell; Haematopoiesis; Stem cell; Myeloid; Biology; Myeloid leukemia; CD34; Bone marrow; Cancer research; Cell biology; Leukemia; Molecular biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001642429,0.0002876422,0.0002176946,0.0001727754,0.0001087331,0.0002903817,0.0002111845,0.0002681314,0.002051726],"category_scores_gemma":[0.0000732047,0.0001598417,0.0002303169,0.0001612331,0.0001650324,0.0001354979,0.0002716571,0.0006067733,0.0006880659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002092194,"about_ca_system_score_gemma":0.0001867302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002962798,"about_ca_topic_score_gemma":0.0007167725,"domain_scores_codex":[0.9998634,0.00002078597,0.00001457272,0.00002666082,0.00004094533,0.00003358923],"domain_scores_gemma":[0.9998997,0.00002547256,0.00002060126,0.0000146994,0.000005540059,0.0000339678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007778541,0.00003699583,0.0001108899,0.00001686402,0.000001902945,0.00001853928,0.000008854112,0.00003406301,0.9984989,0.00006689732,0.00007126142,0.001057031],"study_design_scores_gemma":[0.0000159796,0.0002671956,0.001820982,0.000003721233,0.000008453538,0.0001119047,0.00001146162,0.0005791557,0.9926741,0.00002224392,0.00448275,0.000002076053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865485,0.001800786,0.003488656,0.0001857438,0.00006715982,0.00009477251,0.0009469861,0.0002381034,0.006629309],"genre_scores_gemma":[0.981401,0.0009347803,0.003309643,0.00006787321,0.00002276573,0.00009053961,0.002155469,0.00005293149,0.01196493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002051726,"threshold_uncertainty_score":0.006863773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009976627904671069,"score_gpt":0.2420481429271578,"score_spread":0.2320715150224867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}