{"id":"W2572611801","doi":"10.1016/j.ygyno.2017.01.016","title":"A final report of a phase I study of veliparib (ABT-888) in combination with low-dose fractionated whole abdominal radiation therapy (LDFWAR) in patients with advanced solid malignancies and peritoneal carcinomatosis with a dose escalation in ovarian and fallopian tube cancers","year":2017,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Cancer Institute","keywords":"Medicine; Veliparib; Gastroenterology; Internal medicine; Vomiting; Leukopenia; Nausea; Neutropenia; Mucositis; PARP inhibitor; Anemia; Radiation therapy; Oncology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002220939,0.001000082,0.001710943,0.0002459815,0.0005534202,0.001231268,0.0009511219,0.001748101,0.003473763],"category_scores_gemma":[0.001794106,0.0004238369,0.002607841,0.0002744764,0.0005004053,0.0006693412,0.0003432432,0.003360609,0.001038733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007155447,"about_ca_system_score_gemma":0.001766917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001243495,"about_ca_topic_score_gemma":0.002741867,"domain_scores_codex":[0.9993107,0.0002751764,0.000061176,0.0001176263,0.0000959716,0.0001391729],"domain_scores_gemma":[0.9989952,0.0002602578,0.0001375799,0.0001186728,0.0001489829,0.000339281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3273406,0.05135071,0.01414461,0.003476843,0.00949809,0.003432602,0.000867548,0.007589884,0.1438815,0.001496753,0.08417179,0.3527492],"study_design_scores_gemma":[0.3288308,0.4891495,0.02366747,0.0002109307,0.005392538,0.002440148,0.0002097536,0.002332062,0.04325735,0.001103542,0.1032468,0.000159029],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9164419,0.01395228,0.009472096,0.01213392,0.004041258,0.01162758,0.01681734,0.0005376906,0.01497597],"genre_scores_gemma":[0.9111845,0.009400691,0.01427908,0.01577758,0.001284307,0.006509476,0.02123462,0.0002291346,0.0201006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003473763,"threshold_uncertainty_score":0.01174563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0203187329849931,"score_gpt":0.3261234026123364,"score_spread":0.3058046696273433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}