{"id":"W2572980340","doi":"10.1021/acschembio.6b01071","title":"Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in <i>Mycobacterium tuberculosis</i>","year":2017,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Alberta Glycomics Centre; Centre National de la Recherche Scientifique; Conseil Régional Midi-Pyrénées; Colorado State University","keywords":"Lipoarabinomannan; Mycobacterium tuberculosis; Biosynthesis; Tuberculosis; Mycobacterium; Microbiology; Chemistry; Mycobacterium avium complex; Biology; Computational biology; Biochemistry; Medicine; Bacteria; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333504,0.0003394113,0.0003502684,0.0001988698,0.0001820188,0.000389974,0.0002090477,0.0002979877,0.0002132046],"category_scores_gemma":[0.0002298021,0.0001590239,0.0003707724,0.0003028669,0.000199877,0.0001698859,0.0002600123,0.0003710213,0.0003529766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004313829,"about_ca_system_score_gemma":0.0003493147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001386537,"about_ca_topic_score_gemma":0.001239863,"domain_scores_codex":[0.9998763,0.0000193759,0.00001274854,0.00003416271,0.00003482478,0.00002263044],"domain_scores_gemma":[0.9998529,0.00001800941,0.00005523533,0.00002149495,0.00002035455,0.00003197617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003514619,0.000003897519,0.0002949548,0.00002551809,0.000002144594,0.00004467507,0.00001950863,0.00006414721,0.9984805,0.0000516226,0.000009973767,0.0009678858],"study_design_scores_gemma":[0.00000368551,0.0001045554,0.006050318,0.0000105318,0.00001934271,0.0002958393,0.00004286598,0.000626224,0.9903331,0.00004653018,0.002459519,0.000007369667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900593,0.001328118,0.006802686,0.0001068028,0.00002080076,0.00003667389,0.000770796,0.0001300645,0.0007447262],"genre_scores_gemma":[0.9822434,0.0009555588,0.01277716,0.00007467183,0.0000149646,0.00003200857,0.002108517,0.00005345469,0.001740295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001386537,"threshold_uncertainty_score":0.003129959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584288516288138,"score_gpt":0.245600883831352,"score_spread":0.2297579986684707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}