{"id":"W2573527772","doi":"10.3389/fendo.2017.00002","title":"Non-Genomic Actions of the Androgen Receptor in Prostate Cancer","year":2017,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Prostate cancer; Antiandrogens; Androgen receptor; Signal transduction; Cancer research; Enzalutamide; Androgen; Androgen deprivation therapy; Biology; Cancer; Medicine; Cell biology; Internal medicine; Endocrinology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003372313,0.0006724743,0.000852485,0.001352431,0.0002294756,0.0006725762,0.0006175634,0.0006874196,0.002864989],"category_scores_gemma":[0.0003299771,0.000158669,0.0003232244,0.001349907,0.000474881,0.0008808525,0.0006111093,0.001567559,0.001696091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004942832,"about_ca_system_score_gemma":0.0008698145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007795733,"about_ca_topic_score_gemma":0.001466919,"domain_scores_codex":[0.9998653,0.00002323186,0.00001664436,0.00001915396,0.00005897055,0.00001657354],"domain_scores_gemma":[0.9998666,0.00005405832,0.00001871851,0.000004745055,0.00003766034,0.0000181648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007030481,0.00006736953,0.0002390251,0.01380902,0.00007407717,0.0003248005,0.00007147716,0.0003435746,0.00258234,0.005894229,0.02915716,0.9473667],"study_design_scores_gemma":[0.00001010753,0.00007532133,0.0008546808,0.001563186,0.00005168373,0.00148898,0.00005053215,0.00005020972,0.0003897203,0.001946833,0.9935054,0.00001338869],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009930525,0.998578,0.00008208682,0.0002148976,0.0001956652,0.000002423978,0.00001120127,0.000005586211,0.0008109029],"genre_scores_gemma":[0.0006903823,0.998419,0.00008870353,0.000136163,0.0001920218,0.000002616936,0.0000199232,8.278824e-7,0.0004503693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002864989,"threshold_uncertainty_score":0.009584308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09117992957280395,"score_gpt":0.406325997364343,"score_spread":0.315146067791539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}