{"id":"W2573527772","doi":"10.3389/fendo.2017.00002","title":"Non-Genomic Actions of the Androgen Receptor in Prostate Cancer","year":2017,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Prostate cancer; Antiandrogens; Androgen receptor; Signal transduction; Cancer research; Enzalutamide; Androgen; Androgen deprivation therapy; Biology; Cancer; Medicine; Cell biology; Internal medicine; Endocrinology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009341801,0.0002640316,0.001608392,0.0004922975,0.00006983467,0.000007547325,0.0004117439,0.0001854433,0.00005939893],"category_scores_gemma":[0.00004290907,0.0001639761,0.0002859207,0.0002616867,0.0003960856,0.00003866112,0.0001824385,0.0007657977,0.00001296286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008596081,"about_ca_system_score_gemma":0.001315292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004460413,"about_ca_topic_score_gemma":0.0002080319,"domain_scores_codex":[0.9983346,0.0001138487,0.0004834393,0.0003823154,0.0001347608,0.0005510406],"domain_scores_gemma":[0.9988828,0.00002740248,0.0003100213,0.0006800644,0.00004062392,0.00005904169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001193762,0.0001099676,0.05118493,0.004565732,0.0003704118,0.00009831337,0.0001577865,0.000001424142,0.000005008081,0.000008223118,0.007700645,0.9356782],"study_design_scores_gemma":[0.001418424,0.00007546283,0.001881355,0.004907132,0.0002559405,0.00004867437,0.00006034383,0.000002986575,0.00004770125,0.00002865793,0.9911429,0.0001304012],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001123692,0.9928513,7.789902e-7,0.000388069,0.002019336,0.002120255,0.0001565574,0.000008758436,0.001331316],"genre_scores_gemma":[0.0002447492,0.992286,0.0001253818,0.00001361732,0.0001015041,0.0008743862,0.00006201744,0.00003987943,0.00625243],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9834422,"threshold_uncertainty_score":0.6686752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09117992957280395,"score_gpt":0.406325997364343,"score_spread":0.315146067791539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}