{"id":"W2573920138","doi":"10.1016/j.bbadis.2016.12.022","title":"Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease","year":2017,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Proteostasis; Stress granule; Cell biology; Signal transduction; Cell; Translation (biology); Intracellular; Biology; Crosstalk; Cellular stress response; Neuroscience; Fight-or-flight response; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002404425,0.0008873406,0.001621665,0.0003243131,0.0001688206,0.0001050976,0.001199275,0.0003431224,0.000006558765],"category_scores_gemma":[0.0003424553,0.0008184306,0.001431586,0.0001930871,0.0005927932,0.00002154587,0.0007086526,0.0003343456,0.000004266937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003647858,"about_ca_system_score_gemma":0.001168113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002644533,"about_ca_topic_score_gemma":0.000002742647,"domain_scores_codex":[0.9961702,0.0003975689,0.0008960725,0.001280808,0.0006242197,0.0006311577],"domain_scores_gemma":[0.9953976,0.00006209931,0.001111933,0.002085461,0.0001894776,0.001153385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004561556,0.0007601373,0.00001779995,0.02742467,0.000837082,0.00007200109,0.00001802524,0.00001872948,0.9517319,0.00004844518,0.00009207396,0.01852302],"study_design_scores_gemma":[0.002316334,0.0008369448,0.0007029886,0.01789512,0.006281041,0.00000683437,0.00005469773,0.0004582208,0.9597311,0.0002587031,0.008276016,0.003181967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5413395,0.455872,0.00005867084,0.00004771036,0.00004804579,0.0006912548,0.001905513,0.00001282239,0.0000244709],"genre_scores_gemma":[0.48119,0.5171348,0.0001450312,0.00002505963,0.00004742192,0.0000633695,0.001200686,0.0001117703,0.00008183075],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.06126283,"threshold_uncertainty_score":0.9994267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967473809839123,"score_gpt":0.3146473558532361,"score_spread":0.2949726177548448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}