{"id":"W2573951820","doi":"10.1182/blood.v116.21.229.229","title":"MN1 Inhibits Myeloid Differentiation by Transcriptional Repression of EGR2","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; BC Cancer Agency","funders":"","keywords":"Psychological repression; Retinoic acid; Myeloid; Myeloid leukemia; Cancer research; Biology; Transcription factor; Downregulation and upregulation; Cellular differentiation; Molecular biology; Bone marrow; Leukemia; Cell biology; Cell culture; Gene expression; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007319443,0.00008527652,0.00008027608,0.00001661588,0.00003871763,0.000008671282,0.0001120735,0.0001602782,0.00005633992],"category_scores_gemma":[0.00004794836,0.00007579718,0.0000582825,0.00003846744,0.00005182394,0.000003414488,0.0000261249,0.00009898958,0.000002814369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001277023,"about_ca_system_score_gemma":0.00003669318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003664248,"about_ca_topic_score_gemma":0.000003926605,"domain_scores_codex":[0.999391,0.00001920707,0.0001568107,0.0002081819,0.0001227742,0.0001019845],"domain_scores_gemma":[0.9996211,0.000004678976,0.00007328502,0.0001975449,0.00006546416,0.00003795567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001818873,0.0001837979,0.004316322,0.00002964962,0.00001940273,2.564017e-7,0.00002320232,0.000001219645,0.9941115,0.00009917071,0.0004926113,0.0007046947],"study_design_scores_gemma":[0.0007142992,0.00007649629,0.002832268,0.0000103004,0.00002623752,0.000008710243,0.000008748186,0.000006036684,0.9911556,0.0001145752,0.004956431,0.00009035537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966863,0.0007517933,0.0009427673,0.00003152883,0.0001334925,0.00006415066,0.00002184894,0.000008468567,0.001359684],"genre_scores_gemma":[0.9984266,0.0001125704,0.0003851335,0.00002664426,0.0001501983,0.00001019699,0.0002917799,0.00001131767,0.0005856044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004463819,"threshold_uncertainty_score":0.3090919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003357074311601334,"score_gpt":0.2042264111130257,"score_spread":0.2008693368014244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}