{"id":"W2573951820","doi":"10.1182/blood.v116.21.229.229","title":"MN1 Inhibits Myeloid Differentiation by Transcriptional Repression of EGR2","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; BC Cancer Agency","funders":"","keywords":"Psychological repression; Retinoic acid; Myeloid; Myeloid leukemia; Cancer research; Biology; Transcription factor; Downregulation and upregulation; Cellular differentiation; Molecular biology; Bone marrow; Leukemia; Cell biology; Cell culture; Gene expression; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008387118,0.0003508302,0.0001582843,0.0001453982,0.00009159614,0.0002474586,0.0001907033,0.0001115305,0.001137071],"category_scores_gemma":[0.00006501459,0.00009211108,0.000165231,0.00007970888,0.0001733027,0.00007114419,0.0001810972,0.0003701363,0.0004180636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003490146,"about_ca_system_score_gemma":0.0001836539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005820245,"about_ca_topic_score_gemma":0.001061255,"domain_scores_codex":[0.9999187,0.00001441367,0.000007873432,0.00001699018,0.00001956124,0.00002251928],"domain_scores_gemma":[0.9999381,0.00001219812,0.00002365686,0.000008298797,0.000004688392,0.00001311788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005818707,0.00001854839,0.00008960828,0.00001969901,0.00000247898,0.00001071256,0.0000062723,0.00006369456,0.9991077,0.00005676479,0.00002375792,0.0005425657],"study_design_scores_gemma":[0.000008536933,0.0001124448,0.001782294,0.00000363039,0.000006163058,0.00004931192,0.000009405943,0.0004844857,0.9955547,0.00001584891,0.001971874,0.000001314892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960325,0.001107963,0.001105066,0.00007585794,0.00001219417,0.00001216003,0.0003226342,0.00007800906,0.001253476],"genre_scores_gemma":[0.9949322,0.0006163068,0.0009346134,0.00004156874,0.000004330827,0.00001539083,0.0006355761,0.0000212877,0.002798548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001137071,"threshold_uncertainty_score":0.003803909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003357074311601334,"score_gpt":0.2042264111130257,"score_spread":0.2008693368014244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}