{"id":"W2574083107","doi":"10.1021/acscatal.6b03209","title":"Employing Pd-Catalyzed C–H Arylation in Multicomponent-Multicatalyst Reactions (MC)<sup>2</sup>R: One-Pot Synthesis of Dihydrobenzoquinolines","year":2017,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"H2020 European Research Council; Alphora Research; Natural Sciences and Engineering Research Council of Canada; Alfried Krupp von Bohlen und Halbach-Stiftung; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Catalysis; Enantioselective synthesis; Chemistry; Combinatorial chemistry; Reaction conditions; One-pot synthesis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000819042,0.0004608034,0.0009312708,0.0006131257,0.0005514291,0.0001572241,0.00102954,0.0003347751,0.0006621553],"category_scores_gemma":[0.005608752,0.000518034,0.0004039131,0.0005140392,0.00035324,0.0009071538,0.0004259612,0.0003549743,0.0001340268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003344009,"about_ca_system_score_gemma":0.000113695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004011663,"about_ca_topic_score_gemma":0.0003779121,"domain_scores_codex":[0.9962523,0.00008679761,0.001459927,0.0009165509,0.0007682945,0.0005161476],"domain_scores_gemma":[0.9942282,0.001264276,0.00115493,0.002818956,0.0003363382,0.0001972479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002959592,0.00141823,0.08344505,0.0008141268,0.001135797,0.00001942607,0.001247533,0.01911311,0.8664771,0.0006696211,0.0001062352,0.02525776],"study_design_scores_gemma":[0.001968941,0.00000969771,0.04657769,0.0005321226,0.001184237,0.00002957907,0.0007369409,0.04065964,0.9059817,0.000465908,0.0008823529,0.000971253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932967,0.0001528222,0.002673279,0.0004538326,0.0001206182,0.0002282634,0.0002147853,0.0001806185,0.002679057],"genre_scores_gemma":[0.991285,0.00009590325,0.005695819,0.00001638042,0.0002395471,0.0001691343,0.001387655,0.00009390217,0.00101672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03950448,"threshold_uncertainty_score":0.9997271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04411204858335967,"score_gpt":0.3047805980170823,"score_spread":0.2606685494337227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}