{"id":"W2574083107","doi":"10.1021/acscatal.6b03209","title":"Employing Pd-Catalyzed C–H Arylation in Multicomponent-Multicatalyst Reactions (MC)<sup>2</sup>R: One-Pot Synthesis of Dihydrobenzoquinolines","year":2017,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"H2020 European Research Council; Alphora Research; Natural Sciences and Engineering Research Council of Canada; Alfried Krupp von Bohlen und Halbach-Stiftung; University of Toronto; Deutsche Forschungsgemeinschaft","keywords":"Catalysis; Enantioselective synthesis; Chemistry; Combinatorial chemistry; Reaction conditions; One-pot synthesis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000196796,0.0007075429,0.0003679777,0.0001712889,0.0001535169,0.0002495616,0.0005626021,0.0003182492,0.0008995557],"category_scores_gemma":[0.0001692593,0.0001955466,0.0002348289,0.0001875188,0.0002234249,0.0003744933,0.0004929047,0.0005400103,0.0005762599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002902889,"about_ca_system_score_gemma":0.0002002169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005735316,"about_ca_topic_score_gemma":0.001321507,"domain_scores_codex":[0.9998077,0.00002000733,0.00001615832,0.00006598997,0.00004119029,0.00004887794],"domain_scores_gemma":[0.9999222,0.00001478479,0.00001993815,0.0000169038,0.00001159792,0.0000146524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001457237,0.00004265162,0.0003045752,0.0001686948,0.0000349823,0.0002346137,0.0000423321,0.0005478321,0.9831861,0.0007466952,0.0002291286,0.01431671],"study_design_scores_gemma":[0.0000122786,0.0001724028,0.0004863627,0.000002778363,0.00001673092,0.0002345004,0.000008490802,0.0009103961,0.9954965,0.00004692509,0.002604919,0.000007855383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9199305,0.004651721,0.06244979,0.0001616588,0.0001459167,0.0002701985,0.0005258746,0.00067422,0.01119003],"genre_scores_gemma":[0.9822602,0.0007196092,0.01523061,0.0000326377,0.00001410488,0.0000380072,0.0001507578,0.00003580088,0.001518192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008995557,"threshold_uncertainty_score":0.003009319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04411204858335967,"score_gpt":0.3047805980170823,"score_spread":0.2606685494337227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}