{"id":"W2574295155","doi":"10.1189/jlb.3a0716-295rr","title":"Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes","year":2017,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Government of Jiangsu Province; National Natural Science Foundation of China; University of Saskatchewan","keywords":"Cytotoxic T cell; Biology; CTL*; Priming (agriculture); CD8; Immunology; CD80; Cell biology; T cell; Immune system; CD86; In vitro; CD40","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001053181,0.0003036782,0.0001616868,0.00009801291,0.0000535272,0.0001636247,0.0001148815,0.0001256903,0.0009094735],"category_scores_gemma":[0.00007018463,0.0000597806,0.0001430941,0.00004890076,0.0001002128,0.00008565796,0.0001309087,0.0003283632,0.0001606643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007893718,"about_ca_system_score_gemma":0.00007532683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008982912,"about_ca_topic_score_gemma":0.0001350998,"domain_scores_codex":[0.9998829,0.00002188839,0.000008585584,0.00001917252,0.00002848592,0.00003896361],"domain_scores_gemma":[0.9999522,0.000009172265,0.00001427772,0.000005411812,0.000005514888,0.00001345104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001152653,0.00004957177,0.0001148065,0.00003240453,0.00000371048,0.00003730233,0.000006452008,0.00008129005,0.9972757,0.00005727062,0.00004092182,0.002185329],"study_design_scores_gemma":[0.00003148784,0.0008852836,0.001529532,0.000005166266,0.00002243533,0.0002191801,0.00001206452,0.001161592,0.994019,0.00003654643,0.002075206,0.000002504343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966305,0.0005320273,0.00182913,0.0000266397,0.00003008043,0.00002023005,0.0000481666,0.0000449279,0.0008382882],"genre_scores_gemma":[0.9977176,0.0001674,0.0008209086,0.00003727942,0.00001645359,0.00002196838,0.00007674433,0.0000079455,0.001133839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009094735,"threshold_uncertainty_score":0.003042519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108617388777615,"score_gpt":0.2724899219617342,"score_spread":0.251403748073958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}