{"id":"W2574564768","doi":"10.1182/blood.v126.23.3637.3637","title":"NOTCH1 Induces Differential Epigenomic Patterning and Genomic Organization in Fetal Liver- and Adult Bone Marrow-Derived Hematopoietic Progentiors","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Progenitor cell; Cancer research; Haematopoiesis; Immunophenotyping; Biology; Bone marrow; Myelopoiesis; Immunology; Leukemia; Stem cell; Cell biology; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006711509,0.0001579365,0.0000763998,0.0002078752,0.00007291307,0.0001783238,0.0001031216,0.000101858,0.001020531],"category_scores_gemma":[0.00005558516,0.00008830048,0.0001070429,0.000079032,0.0001113586,0.00007334606,0.0001767217,0.0003062235,0.0002445891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001755829,"about_ca_system_score_gemma":0.0000969716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005460987,"about_ca_topic_score_gemma":0.0009312739,"domain_scores_codex":[0.9999348,0.000008960395,0.000005241106,0.00001674661,0.00001602163,0.00001827202],"domain_scores_gemma":[0.9999131,0.0000169814,0.00002679991,0.000009364961,0.000006910191,0.00002679525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006669429,0.000009970754,0.0003532832,0.000009318304,0.000001727178,0.00002788365,0.00001510593,0.00002550814,0.998373,0.00006911973,0.00001674238,0.001031588],"study_design_scores_gemma":[0.0000120741,0.0003454318,0.01594274,0.000006966009,0.00001169716,0.0002906569,0.00006210495,0.0006068661,0.9810145,0.00003575862,0.001668385,0.000002805986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963447,0.0004426562,0.001542309,0.00001913213,0.00000489154,0.00001438303,0.0004079208,0.00004512678,0.001178806],"genre_scores_gemma":[0.9959905,0.0002740885,0.0009593882,0.00002533501,0.000002912422,0.0000193062,0.0007143837,0.00001510978,0.001998915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001020531,"threshold_uncertainty_score":0.003413975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496989468741909,"score_gpt":0.2354068011827194,"score_spread":0.2204369064953003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}