{"id":"W2574683350","doi":"10.1182/blood.v116.21.2346.2346","title":"Anti-GvHD Effect of Antithymocyte Globulin Is Mediated by Antibodies Binding to T Cells and Regulatory NK Cells, and Less So or Not at All by Antibodies Binding to Other Mononuclear Cell Subsets","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Immunology; Antibody; Polyclonal antibodies; Flow cytometry; Graft-versus-host disease; Peripheral blood mononuclear cell; Pathogenesis; Biology; Cytotoxic T cell; T cell; Immune system; Stem cell; Cell biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005595125,0.0005154099,0.0008594496,0.0002687704,0.0005351444,0.00007091732,0.0003838402,0.0004832731,0.0002776208],"category_scores_gemma":[0.00005484815,0.0004292143,0.0001095269,0.0002602087,0.0005589469,0.0001485996,0.0003782724,0.0003929285,0.0002700317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001573102,"about_ca_system_score_gemma":0.00003641928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003190718,"about_ca_topic_score_gemma":0.00002252165,"domain_scores_codex":[0.997646,0.0001941376,0.0005316325,0.0007311872,0.0001111086,0.0007859445],"domain_scores_gemma":[0.9988806,0.0002912749,0.0002486978,0.0004709569,0.00005342298,0.00005508015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003921815,0.0003020501,0.007329777,0.0002085024,0.0002213926,0.000007870072,0.002248037,0.00000220028,0.9845293,0.00000304982,0.00386025,0.0008953585],"study_design_scores_gemma":[0.003222255,0.0005070601,0.003510807,0.00008329004,0.0001806139,0.00002170772,0.0004387982,0.00000411396,0.9717501,6.65957e-7,0.01974163,0.0005389986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868312,0.01061029,0.000005307358,0.0001143298,0.0006286426,0.0005914036,0.0009486335,0.00008854826,0.0001816192],"genre_scores_gemma":[0.9966918,0.001065672,0.00006149059,0.0003127852,0.000006206123,0.000009518567,0.0001109561,0.00007317269,0.001668464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01588138,"threshold_uncertainty_score":0.9998159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006812360158115075,"score_gpt":0.2197137698620831,"score_spread":0.212901409703968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}