{"id":"W2574683350","doi":"10.1182/blood.v116.21.2346.2346","title":"Anti-GvHD Effect of Antithymocyte Globulin Is Mediated by Antibodies Binding to T Cells and Regulatory NK Cells, and Less So or Not at All by Antibodies Binding to Other Mononuclear Cell Subsets","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Immunology; Antibody; Polyclonal antibodies; Flow cytometry; Graft-versus-host disease; Peripheral blood mononuclear cell; Pathogenesis; Biology; Cytotoxic T cell; T cell; Immune system; Stem cell; Cell biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656063,0.0002518732,0.0003954402,0.0002786748,0.0002334575,0.0002760163,0.0001180453,0.0001940316,0.003677064],"category_scores_gemma":[0.0002226752,0.000135809,0.0002086261,0.0002813503,0.0002422779,0.0001650078,0.0001530572,0.0002362705,0.0004952328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000233702,"about_ca_system_score_gemma":0.0001724544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002283869,"about_ca_topic_score_gemma":0.0002291903,"domain_scores_codex":[0.9998873,0.00002077831,0.00001282691,0.00002756892,0.00002189463,0.00002953122],"domain_scores_gemma":[0.9998362,0.00005445286,0.00004936037,0.00001350578,0.00001251103,0.00003397452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004526058,0.0004743874,0.8544918,0.000253372,0.0001363218,0.003376821,0.0001702364,0.0002867534,0.0977454,0.0002634566,0.0005492452,0.03772608],"study_design_scores_gemma":[0.0003187102,0.005618756,0.9474182,0.00004499121,0.0002496442,0.02171309,0.0001686386,0.0003891128,0.01873807,0.000130103,0.00520025,0.00001057952],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967603,0.001190753,0.0002043918,0.00001995873,0.000005646287,0.00001880592,0.0001143506,0.000006386309,0.001679462],"genre_scores_gemma":[0.9987947,0.0004244684,0.0001269671,0.00003819203,0.00001487242,0.0000132627,0.0002708351,0.000002290748,0.0003144491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003677064,"threshold_uncertainty_score":0.01230103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006812360158115075,"score_gpt":0.2197137698620831,"score_spread":0.212901409703968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}