{"id":"W2574943126","doi":"10.1111/all.13101","title":"Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2‐induced airway inflammation and remodeling","year":2016,"lang":"en","type":"article","venue":"Allergy","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; University of Manitoba","funders":"Deutsche Forschungsgemeinschaft","keywords":"Medicine; Airway; Inflammation; Spleen; Immunology; Tyrosine kinase; Internal medicine; Anesthesia; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000147491,0.0005543687,0.0003779752,0.0002185396,0.0001483572,0.0001863803,0.0002113063,0.0002339624,0.002233912],"category_scores_gemma":[0.0001016084,0.000118784,0.0003159477,0.00009961501,0.0003244297,0.0001686943,0.0001680144,0.001032603,0.0004907909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002527979,"about_ca_system_score_gemma":0.0003281238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002571189,"about_ca_topic_score_gemma":0.0004894506,"domain_scores_codex":[0.9998932,0.0000128955,0.000009189233,0.00001664544,0.00002493716,0.00004318252],"domain_scores_gemma":[0.9999092,0.000008742341,0.00003070764,0.000007735165,0.000007432758,0.00003622083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001051016,0.0001959899,0.0002480525,0.0001183212,0.00001524416,0.00005378804,0.0000112062,0.0001377276,0.9947897,0.00006062115,0.0001386197,0.00317969],"study_design_scores_gemma":[0.0003330648,0.003977851,0.009409887,0.00002787518,0.00006158408,0.000378162,0.00004369198,0.001472268,0.9813499,0.00009535281,0.002841611,0.000008745315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941043,0.003122328,0.0009698129,0.0001151268,0.00006221182,0.00002903362,0.0002424225,0.0001298158,0.001224962],"genre_scores_gemma":[0.995909,0.001490965,0.0006254736,0.00003696471,0.00002289234,0.00004357526,0.000366768,0.00001913161,0.001485207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002233912,"threshold_uncertainty_score":0.00747323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019593051617636,"score_gpt":0.1961200153476397,"score_spread":0.1859240848314634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}