{"id":"W2574943126","doi":"10.1111/all.13101","title":"Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2‐induced airway inflammation and remodeling","year":2016,"lang":"en","type":"article","venue":"Allergy","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; University of Manitoba","funders":"Deutsche Forschungsgemeinschaft","keywords":"Medicine; Airway; Inflammation; Spleen; Immunology; Tyrosine kinase; Internal medicine; Anesthesia; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100367,0.0001390117,0.0001617642,0.0000845953,0.0001673013,0.00001661932,0.0000330679,0.0002168454,0.0003651407],"category_scores_gemma":[0.00004188564,0.0001044889,0.00001914723,0.0000521555,0.00009680443,0.0001325157,0.00005510286,0.0001047553,0.00004531856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002461274,"about_ca_system_score_gemma":0.00002106184,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004620843,"about_ca_topic_score_gemma":0.000203021,"domain_scores_codex":[0.9992164,0.00006750777,0.0002201997,0.0002873313,0.00002992376,0.000178575],"domain_scores_gemma":[0.9995936,0.00006738598,0.0001092371,0.0001405041,0.00006116094,0.0000281771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009128368,0.0000185378,0.00006796588,0.000007991973,0.00003709612,0.000002036701,0.0001390986,0.000001784102,0.9482998,0.0003713705,0.0003248682,0.05063821],"study_design_scores_gemma":[0.00349007,0.000334285,0.002150172,0.0001647265,0.00002741011,0.00003310621,0.00006768556,0.00009308133,0.9470119,0.0005682813,0.04576891,0.0002904097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957071,0.001097772,0.001036998,0.0008309679,0.0001934207,0.00023255,0.00003724872,0.00006171753,0.000802244],"genre_scores_gemma":[0.9982992,0.0004843338,0.0001054116,0.00003667023,0.00007681201,0.00001986848,0.0001328916,0.000009878063,0.0008348765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0503478,"threshold_uncertainty_score":0.4260933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019593051617636,"score_gpt":0.1961200153476397,"score_spread":0.1859240848314634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}