{"id":"W2575001609","doi":"10.1182/blood.v126.23.3976.3976","title":"A Phase 1 Study of the Anti-CD37 Antibody-Drug Conjugate AGS67E in Advanced Lymphoid Malignancies. Interim Results","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Neutropenia; Lymphoma; Internal medicine; Gastroenterology; Follicular lymphoma; Mycosis fungoides; Antibody-drug conjugate; Mantle cell lymphoma; Alemtuzumab; Oncology; Immunology; Antibody; Toxicity; Transplantation; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001161222,0.0009355035,0.001055149,0.0002602517,0.0002838395,0.0006024474,0.0006610438,0.0008838241,0.003822649],"category_scores_gemma":[0.0004236133,0.0003120682,0.0007739047,0.0001920959,0.0003461577,0.0003838702,0.0002338373,0.001483468,0.0008734455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006291853,"about_ca_system_score_gemma":0.001087804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005987578,"about_ca_topic_score_gemma":0.001464555,"domain_scores_codex":[0.9997566,0.00009710184,0.00001206051,0.00003363616,0.00003036225,0.00007017146],"domain_scores_gemma":[0.9997439,0.00003877623,0.00004448766,0.00002094276,0.00002922847,0.0001227311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3214971,0.06615108,0.01095678,0.002341633,0.001584503,0.001820333,0.0004991485,0.005866647,0.1775339,0.001685218,0.0351516,0.3749121],"study_design_scores_gemma":[0.2631705,0.6753898,0.01591722,0.0001198319,0.0005595315,0.001321299,0.00006862958,0.002030917,0.02100802,0.0007297688,0.01965365,0.00003084993],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723533,0.007880807,0.002293757,0.00147221,0.000423275,0.005409412,0.00316861,0.0002762845,0.006722242],"genre_scores_gemma":[0.9712301,0.004789766,0.003549307,0.001962259,0.0002528079,0.004054852,0.005660668,0.00006325847,0.008437001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003822649,"threshold_uncertainty_score":0.01278806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04012392533851929,"score_gpt":0.360985348569889,"score_spread":0.3208614232313697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}