{"id":"W2575001609","doi":"10.1182/blood.v126.23.3976.3976","title":"A Phase 1 Study of the Anti-CD37 Antibody-Drug Conjugate AGS67E in Advanced Lymphoid Malignancies. Interim Results","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Neutropenia; Lymphoma; Internal medicine; Gastroenterology; Follicular lymphoma; Mycosis fungoides; Antibody-drug conjugate; Mantle cell lymphoma; Alemtuzumab; Oncology; Immunology; Antibody; Toxicity; Transplantation; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009173888,0.0002197072,0.0005663237,0.0001629704,0.00004089805,0.00001820524,0.0004200771,0.00007464981,0.00001207455],"category_scores_gemma":[0.0009926211,0.0001506756,0.00009517041,0.0006791831,0.0001923127,0.0001059248,0.0003482438,0.000225659,0.00002929372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001628879,"about_ca_system_score_gemma":0.004441035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001660278,"about_ca_topic_score_gemma":0.0002451206,"domain_scores_codex":[0.9973559,0.0001949307,0.0006989872,0.0004601557,0.0008090045,0.0004810458],"domain_scores_gemma":[0.9981272,0.0001213102,0.000201089,0.00107003,0.0002664456,0.0002139805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.0234017,0.1631189,0.07890069,0.001428817,0.001435488,0.007765515,0.07148022,0.0003720415,0.6374347,0.0001745663,0.005629069,0.008858372],"study_design_scores_gemma":[0.7582542,0.004075382,0.006695725,0.001082934,0.0002704085,0.0007486169,0.009036506,0.001517879,0.2160988,0.0000458161,0.001815564,0.0003581615],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951913,0.00050911,0.000002068521,0.0002104395,0.0002121759,0.001446691,0.0000351264,0.00004349972,0.002349583],"genre_scores_gemma":[0.9986942,0.00005200966,0.00007807578,0.0001061211,0.00007793958,0.00004096098,0.00001759589,0.00003547314,0.0008976582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7348525,"threshold_uncertainty_score":0.7878205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04012392533851929,"score_gpt":0.360985348569889,"score_spread":0.3208614232313697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}