{"id":"W2575174870","doi":"10.1182/blood.v110.11.2203.2203","title":"G-CSF Induces Expression of Both Hepatocyte Growth Factor (HGF) and Its Receptor (c-Met) in Human Hematopoietic Stem/Progenitor Cells and Mature Myeloid Cells - Novel Evidence That during Mobilization the HGF-c-Met Axis Counterbalances G-CSF-Induced Attenuation of the SDF-1-CXCR4 Axis.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Liver physiology and pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"","keywords":"Hepatocyte growth factor; CD34; Haematopoiesis; Stromal cell; Stem cell; Progenitor cell; Bone marrow; CXCR4; Stem cell factor; Biology; Stromal cell-derived factor 1; Cell biology; Cancer research; Molecular biology; Immunology; Receptor; Chemokine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005131401,0.0002330926,0.0004445699,0.0001165809,0.0001507382,0.0000184355,0.0002158641,0.0003133562,0.00001669943],"category_scores_gemma":[0.00009237489,0.0001441327,0.00006262595,0.0002516938,0.0001761572,0.00031605,0.0001391374,0.0003468152,0.00000131479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002563978,"about_ca_system_score_gemma":0.000050153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004784885,"about_ca_topic_score_gemma":0.00002551174,"domain_scores_codex":[0.9983744,0.0002068157,0.0004623533,0.0003898476,0.0003142511,0.0002523448],"domain_scores_gemma":[0.9985799,0.0003314423,0.0005377482,0.0003267575,0.0001609066,0.00006330007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001852478,0.0002179324,0.1253314,0.0005925538,0.00003390312,0.000003303778,0.003477925,9.924438e-7,0.8700794,0.00002046132,0.000006102574,0.00005077026],"study_design_scores_gemma":[0.001312485,0.0002498902,0.2624288,0.0008048422,0.00007966242,0.00002383857,0.000641392,0.000005692694,0.7343274,0.00002439125,0.000001825038,0.00009984907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99732,0.001379243,0.00001304466,0.00007280391,0.0001933638,0.0009374901,0.00004916478,0.00001911772,0.00001578395],"genre_scores_gemma":[0.9993138,0.0003246723,0.00009283398,0.00007161722,0.0001040632,0.00002789442,0.000009527767,0.00002117135,0.00003440281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1370973,"threshold_uncertainty_score":0.587756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03320760917374155,"score_gpt":0.2662456748866757,"score_spread":0.2330380657129342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}