{"id":"W2575174870","doi":"10.1182/blood.v110.11.2203.2203","title":"G-CSF Induces Expression of Both Hepatocyte Growth Factor (HGF) and Its Receptor (c-Met) in Human Hematopoietic Stem/Progenitor Cells and Mature Myeloid Cells - Novel Evidence That during Mobilization the HGF-c-Met Axis Counterbalances G-CSF-Induced Attenuation of the SDF-1-CXCR4 Axis.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Liver physiology and pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"","keywords":"Hepatocyte growth factor; CD34; Haematopoiesis; Stromal cell; Stem cell; Progenitor cell; Bone marrow; CXCR4; Stem cell factor; Biology; Stromal cell-derived factor 1; Cell biology; Cancer research; Molecular biology; Immunology; Receptor; Chemokine; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000081716,0.0001673376,0.00008305175,0.0002294686,0.00008116802,0.0001246008,0.00004842357,0.0001133749,0.0008590225],"category_scores_gemma":[0.00007634671,0.00007842285,0.0001255974,0.0001253652,0.0001020384,0.00006490538,0.0001335258,0.0001880052,0.0002642693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001666517,"about_ca_system_score_gemma":0.0001511095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009345427,"about_ca_topic_score_gemma":0.001381787,"domain_scores_codex":[0.9999229,0.00001608575,0.000005285435,0.00000988055,0.00001968886,0.0000261894],"domain_scores_gemma":[0.9999576,0.000007856202,0.000008184426,0.000005667943,0.000005992042,0.00001472084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001844995,0.0000154742,0.0002828033,0.00001660716,0.000002104273,0.00004913823,0.00001171548,0.00001617709,0.9982567,0.00003207417,0.00003382362,0.001098917],"study_design_scores_gemma":[0.00006705659,0.0008278454,0.04134073,0.000008854,0.00002132627,0.000712528,0.0000538912,0.0007386895,0.9520801,0.00007474179,0.00406919,0.00000495049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966775,0.001271048,0.0009121401,0.00004845869,0.00001135567,0.00003895744,0.0003605572,0.00002033106,0.0006594813],"genre_scores_gemma":[0.9959025,0.0004933806,0.001294995,0.00004158465,0.000009621234,0.00004811856,0.000888216,0.000005805687,0.001315917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009345427,"threshold_uncertainty_score":0.002873719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03320760917374155,"score_gpt":0.2662456748866757,"score_spread":0.2330380657129342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}