{"id":"W2575316509","doi":"10.1097/tp.0000000000001638","title":"Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice","year":2017,"lang":"en","type":"article","venue":"Transplantation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Islet; Transplantation; Apoptosis; Endocrinology; Internal medicine; Type 1 diabetes; Renal capsule; Andrology; Terminal deoxynucleotidyl transferase; Medicine; TUNEL assay; Biology; Diabetes mellitus; Immunohistochemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003744592,0.0001202567,0.0002209543,0.0001169054,0.0001019373,0.00002128229,0.00003865998,0.00006064718,0.000003751488],"category_scores_gemma":[0.0000294238,0.00009263919,0.00002772362,0.0000573813,0.00005600643,0.0001128126,0.000006357656,0.0001049475,0.00000153581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004624337,"about_ca_system_score_gemma":0.00001917733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046235,"about_ca_topic_score_gemma":0.0006604852,"domain_scores_codex":[0.9991677,0.0001284817,0.0002254936,0.0002131785,0.0001391645,0.000126015],"domain_scores_gemma":[0.9995382,0.000150327,0.00007409851,0.0001558751,0.00002567641,0.00005576646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001075236,0.0001231761,0.1437711,0.001119088,0.00001657969,0.00001576286,0.002907285,0.00001294736,0.8501659,0.0001264588,0.000001326152,0.0006651697],"study_design_scores_gemma":[0.004041416,0.0001873215,0.5580529,0.0003985541,0.00007095152,0.000006393558,0.00006351612,0.00003743899,0.4370512,0.00003028621,0.000003171483,0.00005689737],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983934,0.00005127921,0.00009198692,0.000159265,0.00006518103,0.000994565,0.00007929807,0.0000102956,0.0001547159],"genre_scores_gemma":[0.9994487,0.0001679277,0.00009519715,0.00007212827,0.00001953441,0.0000907898,0.00005472963,0.000009546036,0.00004144389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4142818,"threshold_uncertainty_score":0.3777717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009534532395489162,"score_gpt":0.2630838632672023,"score_spread":0.2535493308717132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}