{"id":"W2575535966","doi":"10.1093/jb/mvw102","title":"PRMT2 interacts with splicing factors and regulates the alternative splicing of <i>BCL-X</i>","year":2017,"lang":"en","type":"article","venue":"The Journal of Biochemistry","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of British Columbia","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; U.S. Department of Veterans Affairs","keywords":"Alternative splicing; RNA splicing; Cell biology; Biology; Genetics; Gene isoform; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003184795,0.0001295847,0.0001540304,0.00001598979,0.0001870666,0.00003762901,0.0003943377,0.00007672775,0.000003153708],"category_scores_gemma":[0.0001009373,0.0000657794,0.00006167856,0.00002722189,0.0002875447,0.00001103827,0.0001213154,0.0001669416,1.346637e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001920264,"about_ca_system_score_gemma":0.00006468824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008496784,"about_ca_topic_score_gemma":0.00002381364,"domain_scores_codex":[0.9993361,0.00003162031,0.0002433895,0.0001076649,0.0001639067,0.0001173645],"domain_scores_gemma":[0.9984086,0.00004251922,0.0008868077,0.0004521685,0.0001650894,0.00004479865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002359448,0.00001223683,0.003368855,0.00002197928,0.0001556929,9.61673e-7,0.0002912106,0.0003721976,0.994506,0.000002086788,0.0002092923,0.0008235436],"study_design_scores_gemma":[0.0004129113,0.0001421285,0.009203812,0.0001867518,0.00008789675,0.0001810568,0.0003219978,0.00007116953,0.9891044,0.00003742008,0.0001686398,0.00008174928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978436,0.001039802,0.000135708,0.0005520486,0.00008262384,0.00006882496,0.000004215448,0.000001408195,0.0002717596],"genre_scores_gemma":[0.9989693,0.0004310299,0.00007046673,0.00002522858,0.000285083,5.510924e-7,0.000003132691,0.00001378028,0.0002014728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005834957,"threshold_uncertainty_score":0.2682406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007642150518210092,"score_gpt":0.2446800170091853,"score_spread":0.2370378664909752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}