{"id":"W2576631206","doi":"10.3174/ajnr.a5061","title":"Predictive Utility of Marketed Volumetric Software Tools in Subjects at Risk for Alzheimer Disease: Do Regions Outside the Hippocampus Matter?","year":2017,"lang":"en","type":"article","venue":"American Journal of Neuroradiology","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; National Institutes of Health; Genentech; National Institute of Neurological Disorders and Stroke; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; University of California, San Diego; Alzheimer's Association; Fujirebio US; Pfizer; Biogen; BioClinica; F. Hoffmann-La Roche; Radiological Society of North America; University of Southern California; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Meso Scale Diagnostics; Foundation for the National Institutes of Health","keywords":"Medicine; Hippocampus; Disease; Alzheimer's disease; Neuroscience; Software; Pathology; Internal medicine; Computer science; Psychology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004093931,0.0005133501,0.0003782805,0.001180174,0.0001565454,0.0007086361,0.0006558879,0.0005218927,0.001519006],"category_scores_gemma":[0.01954854,0.0002055446,0.0005345775,0.0006763503,0.0003703906,0.000718802,0.0003748286,0.0005291119,0.0003600159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002531791,"about_ca_system_score_gemma":0.0003425476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001175346,"about_ca_topic_score_gemma":0.002464246,"domain_scores_codex":[0.998787,0.0005082508,0.0001016468,0.0001836642,0.0003545918,0.0000648729],"domain_scores_gemma":[0.9840795,0.008736363,0.004145415,0.0007134592,0.001827725,0.0004974591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001692924,0.0001051834,0.9604675,0.0000477985,0.0001719892,0.00004610377,0.00007956352,0.0006391164,0.0007046726,0.00006298814,0.0005120194,0.03547019],"study_design_scores_gemma":[0.0001492823,0.001521942,0.9825167,0.00007888571,0.0003184064,0.0006719829,0.0001628651,0.0108108,0.002563243,0.0003835348,0.000782455,0.00003977547],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961893,0.001091732,0.001549133,0.000191915,0.00002204777,0.00001687256,0.0003744091,0.00007372366,0.0004908327],"genre_scores_gemma":[0.9966828,0.0002196313,0.002482597,0.00004874279,0.00003266711,0.00001557255,0.0003640099,0.00001521157,0.0001386364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004093931,"threshold_uncertainty_score":0.02165103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03523905759693458,"score_gpt":0.3318282914781507,"score_spread":0.2965892338812161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}