{"id":"W2577148680","doi":"10.1136/sextrans-2016-052870","title":"A double-edged sword: does highly active antiretroviral therapy contribute to syphilis incidence by impairing immunity to<i>Treponema pallidum</i>?","year":2017,"lang":"en","type":"review","venue":"Sexually Transmitted Infections","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; McMaster University; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Syphilis; Medicine; Immunology; Chlamydia; Treponema; Men who have sex with men; Incidence (geometry); Population; Transmission (telecommunications); Gonorrhea; Virology; Sexually transmitted disease; Human immunodeficiency virus (HIV); Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002033275,0.0004263798,0.001006655,0.0008506711,0.000343849,0.001504469,0.001040713,0.002334448,0.003303651],"category_scores_gemma":[0.01113417,0.0002958894,0.001854952,0.0007138494,0.001125974,0.001807153,0.0005882274,0.0008865745,0.0003131002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004678567,"about_ca_system_score_gemma":0.001312062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002117603,"about_ca_topic_score_gemma":0.001585958,"domain_scores_codex":[0.9991956,0.0004133402,0.00007576725,0.0001488365,0.00009776944,0.00006868647],"domain_scores_gemma":[0.9898059,0.007436248,0.001700691,0.0003342393,0.0004480854,0.0002747859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.008197714,0.001368396,0.4643655,0.0208361,0.01079977,0.01027979,0.001590517,0.02175173,0.007571429,0.07141662,0.01271448,0.369108],"study_design_scores_gemma":[0.00130122,0.005168662,0.4183853,0.007785743,0.0130312,0.01014355,0.006198037,0.1265272,0.007662924,0.3700922,0.03334909,0.0003549239],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6419739,0.2149467,0.036972,0.08481491,0.001841136,0.0003394551,0.001418168,0.0001286669,0.01756516],"genre_scores_gemma":[0.9617497,0.02718378,0.002851901,0.005220471,0.00136387,0.00005666216,0.0001561693,0.00001533252,0.00140219],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003303651,"threshold_uncertainty_score":0.01105177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05502287792720334,"score_gpt":0.3703694284687666,"score_spread":0.3153465505415633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}