{"id":"W2577626296","doi":"10.1128/jvi.00025-17","title":"Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation","year":2017,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Institut National de la Recherche Scientifique","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; National Natural Science Foundation of China","keywords":"Biology; Herpes simplex virus; Promoter; Transcription (linguistics); DNA; Transcription factor; Molecular biology; Innate immune system; Gene; Immune system; Virus; Gene expression; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007391811,0.0001728765,0.0003508002,0.00009847441,0.0007989354,0.00007420345,0.0004009797,0.0002765172,0.0003785535],"category_scores_gemma":[0.00048286,0.000113141,0.0001642106,0.00002837343,0.0004652685,0.0002588491,0.0001245846,0.0005617881,0.00009014636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004277482,"about_ca_system_score_gemma":0.00008362811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007732177,"about_ca_topic_score_gemma":0.00002604103,"domain_scores_codex":[0.9984121,0.0005356955,0.0005128452,0.0001396709,0.00005124387,0.000348418],"domain_scores_gemma":[0.9980629,0.0005361383,0.001013528,0.0002344948,0.0001311564,0.00002178741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009189993,0.00005693559,0.00007570923,0.000003618802,0.0001489403,0.00001604928,0.0003884794,0.000003119046,0.9375172,0.00009436801,0.00577672,0.0549999],"study_design_scores_gemma":[0.0009725907,0.0005042076,0.001555053,0.00004303368,0.00003031364,0.0005905594,0.000322667,0.00001102369,0.8712385,0.0002224318,0.1244065,0.0001031333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935746,0.00101037,0.0005241802,0.003569694,0.0006559572,0.00007749403,0.00001192033,0.00001315314,0.0005625876],"genre_scores_gemma":[0.998409,0.00006436751,0.00003215472,0.0006382704,0.0001526125,7.958243e-7,0.000007057725,0.00001703238,0.0006787172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1186298,"threshold_uncertainty_score":0.6144845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574499985576313,"score_gpt":0.2629035727624358,"score_spread":0.2471585729066726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}