{"id":"W2578022531","doi":"10.1016/j.mito.2017.01.003","title":"RSM22, mtYsxC and PNKD-like proteins are required for mitochondrial translation in Trypanosoma brucei","year":2017,"lang":"en","type":"article","venue":"Mitochondrion","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Johns Hopkins University","keywords":"Mitochondrial ribosome; Ribosome; Trypanosoma brucei; Ribosomal protein; Biology; Eukaryotic Ribosome; Translation (biology); Mitochondrion; Cell biology; Transfer RNA; Protein biosynthesis; Ribosomal RNA; Protein subunit; Eukaryotic Small Ribosomal Subunit; Biochemistry; Genetics; RNA; Messenger RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006890084,0.0003133003,0.0002208671,0.0002344439,0.0001987239,0.0003037181,0.00009831601,0.0002199477,0.0006502536],"category_scores_gemma":[0.0001754698,0.00009686864,0.0001808381,0.0002148371,0.0001737967,0.0001289883,0.0001707752,0.0001811657,0.0003956421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002720301,"about_ca_system_score_gemma":0.0001863281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009931286,"about_ca_topic_score_gemma":0.001627032,"domain_scores_codex":[0.9999251,0.00001060643,0.00001215455,0.00001560595,0.00002623493,0.00001021223],"domain_scores_gemma":[0.9999032,0.00001453457,0.00003531172,0.000008125591,0.000008988765,0.00002990115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005919133,0.000006799376,0.0006113221,0.00002671165,0.000002919657,0.0001599908,0.00001444702,0.00003236487,0.9984583,0.00004365906,0.00002621097,0.0005581037],"study_design_scores_gemma":[0.00002894739,0.0001764387,0.07587667,0.00002511642,0.00004265461,0.002082912,0.000162827,0.001921734,0.9141935,0.0001430574,0.005331621,0.00001448258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963759,0.001580373,0.0009250012,0.0000868471,0.00001252209,0.000006034642,0.0005170835,0.00004926762,0.0004470996],"genre_scores_gemma":[0.9948185,0.000520418,0.001554717,0.00003707543,0.000006682223,0.00001572994,0.001880938,0.00002589655,0.001140119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009931286,"threshold_uncertainty_score":0.002175331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02580242040194604,"score_gpt":0.2707577281937156,"score_spread":0.2449553077917695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}