{"id":"W2578409681","doi":"10.1002/cbic.201600708","title":"An Exceptionally Selective DNA Cooperatively Binding Two Ca<sup>2+</sup> Ions","year":2017,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council","keywords":"DNA; Chemistry; Ion; Biophysics; Combinatorial chemistry; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002928181,0.0004362764,0.0003685633,0.0001873226,0.0001656869,0.0003984073,0.0005860737,0.0008562942,0.0006599621],"category_scores_gemma":[0.0007360129,0.0003077648,0.0002717279,0.0001660119,0.0004131152,0.000311422,0.0003639311,0.0005216291,0.0005249592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003420274,"about_ca_system_score_gemma":0.0003059367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005605934,"about_ca_topic_score_gemma":0.0007587037,"domain_scores_codex":[0.9994788,0.00006843651,0.00002855133,0.0002181114,0.0001441565,0.00006196926],"domain_scores_gemma":[0.9996009,0.000105363,0.00008563388,0.00003587091,0.00008940629,0.00008284658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003771136,0.000008850835,0.00009561254,0.00002819686,0.000003732659,0.00002562838,0.00001232829,0.00007792059,0.9978333,0.00007392953,0.00003399936,0.001768904],"study_design_scores_gemma":[0.000009572632,0.00009091923,0.0003032384,0.000002096556,0.000005253324,0.0001434442,0.000005310886,0.0008931572,0.9970919,0.00002410515,0.00142565,0.000005296622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9212125,0.002371528,0.07046688,0.0004492838,0.0002212256,0.0001483506,0.0003653089,0.0009836821,0.003781221],"genre_scores_gemma":[0.9277474,0.0004279627,0.06328627,0.0001815665,0.00002814849,0.0000921606,0.0003911589,0.00005699431,0.007788257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008562942,"threshold_uncertainty_score":0.00248158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01499380150899542,"score_gpt":0.3130167551598885,"score_spread":0.2980229536508931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}