{"id":"W2579151267","doi":"","title":"The Case for Selection at CCR5-Δ32","year":2005,"lang":"en","type":"article","venue":"NSUWorks (Nova Southeastern University)","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University; Damon Runyon Cancer Research Foundation; Cancer Research Institute","keywords":"Biology; Locus (genetics); Genetics; Allele; Linkage disequilibrium; Chemokine receptor CCR5; Evolutionary biology; Selection (genetic algorithm); Genetic variation; Balancing selection; Chemokine receptor; Gene; Haplotype; Receptor; Chemokine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001579938,0.0002186053,0.0003538934,0.0002751149,0.0007285536,0.001101069,0.0005541999,0.00107207,0.005540199],"category_scores_gemma":[0.002689107,0.0001337743,0.0002381622,0.0002944166,0.001149142,0.0008799701,0.0005354625,0.001289598,0.0006900938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003520717,"about_ca_system_score_gemma":0.0004171311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001408458,"about_ca_topic_score_gemma":0.001713609,"domain_scores_codex":[0.9992352,0.0001318326,0.00004027944,0.0002829423,0.0001459989,0.0001637985],"domain_scores_gemma":[0.9983811,0.0006632887,0.000218054,0.0002807713,0.0001654494,0.0002912952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002114102,0.0002838523,0.3247313,0.001040191,0.0004390361,0.007287433,0.002274749,0.001858022,0.2891857,0.1401742,0.01821911,0.2123924],"study_design_scores_gemma":[0.0004170087,0.00145118,0.612174,0.00061991,0.0004016415,0.0195322,0.004588271,0.006853466,0.04933657,0.1072322,0.1971795,0.0002141267],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9200077,0.009919886,0.008879519,0.01967327,0.001193736,0.00004311297,0.0003461213,0.0001699314,0.03976683],"genre_scores_gemma":[0.9892966,0.001740817,0.001697472,0.004174801,0.0002290988,0.00001507909,0.0001825891,0.00002611469,0.002637291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005540199,"threshold_uncertainty_score":0.01853377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02112927041930463,"score_gpt":0.2393013342014096,"score_spread":0.218172063782105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}