{"id":"W2580170403","doi":"10.1182/blood.v104.11.369.369","title":"Regulation of Oxidative Stress by ATM Is Required for the Self-Renewal of Haematopoietic Stem Cells.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Haematopoiesis; Stem cell; Biology; Bone marrow; Telomere; Stromal cell; Progenitor cell; Immunology; Senescence; Cell biology; Hematopoietic stem cell; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330894,0.0002982771,0.0001280757,0.0002158537,0.0001618594,0.0002421661,0.0001982969,0.0002177812,0.001655108],"category_scores_gemma":[0.0001076002,0.0001184757,0.0001774901,0.00009159657,0.0001677584,0.0002191888,0.0002159585,0.0003482746,0.0003066331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001466466,"about_ca_system_score_gemma":0.0000960077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001357194,"about_ca_topic_score_gemma":0.0001761034,"domain_scores_codex":[0.9998906,0.00001847901,0.0000134995,0.0000256679,0.00003313112,0.0000186107],"domain_scores_gemma":[0.999844,0.00001697356,0.00006730171,0.00001460719,0.00001567428,0.00004134098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005642545,0.00001259287,0.0003427477,0.00002279244,0.000003183707,0.00003827623,0.000005358145,0.000009614686,0.9987512,0.00005053489,0.00002013094,0.0006871451],"study_design_scores_gemma":[0.00001413905,0.0003321234,0.03424912,0.00001396226,0.00002329265,0.0005108257,0.00003246917,0.0005689693,0.9617044,0.0001382247,0.002408773,0.000003750176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941241,0.002767621,0.001615584,0.0000850037,0.00004803988,0.00002044319,0.0003780947,0.00007947577,0.0008816716],"genre_scores_gemma":[0.9962135,0.000636737,0.0009587486,0.00003909831,0.00001301498,0.00002451605,0.0004868749,0.000007744969,0.001619614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001655108,"threshold_uncertainty_score":0.005536854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008311562879247671,"score_gpt":0.2212734236813045,"score_spread":0.2129618608020568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}