{"id":"W2580443921","doi":"10.1182/blood.v124.21.4027.4027","title":"Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Oxidative stress; DMT1; Biology; Erythropoiesis; Red blood cell; Reactive oxygen species; GATA1; Erythroblast; Apoptosis; Anemia; Cell biology; Molecular biology; Haematopoiesis; Immunology; Internal medicine; Biochemistry; Stem cell; Transporter; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001751011,0.0004623452,0.0002596794,0.0005254211,0.0001290982,0.0002526483,0.0001828614,0.0003568068,0.0008298627],"category_scores_gemma":[0.0001769622,0.000148436,0.0001964807,0.0002005553,0.0002651395,0.0001501731,0.000278721,0.0004431893,0.0001255844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002361448,"about_ca_system_score_gemma":0.0001236613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003627121,"about_ca_topic_score_gemma":0.0002888049,"domain_scores_codex":[0.9999018,0.00002104408,0.00001305478,0.0000255827,0.00002597697,0.00001243778],"domain_scores_gemma":[0.9998598,0.00000837641,0.000081202,0.000007685482,0.0000151751,0.00002779541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001138508,0.00008598705,0.01698224,0.0001964363,0.00005734717,0.00162745,0.00007011857,0.0001148474,0.971508,0.0002971303,0.0002863803,0.007635534],"study_design_scores_gemma":[0.0001674277,0.001437681,0.2740799,0.00008616355,0.0003401345,0.01865257,0.0001819388,0.002945565,0.6923245,0.00123238,0.008531497,0.00002013377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860229,0.009735451,0.002818015,0.0003030567,0.00004232831,0.0000332974,0.0002378145,0.00007921857,0.0007277798],"genre_scores_gemma":[0.9954427,0.002087611,0.001276976,0.000103233,0.00002518323,0.00001691065,0.0002068217,0.000009777556,0.000830828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008298627,"threshold_uncertainty_score":0.002776206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007105757000375106,"score_gpt":0.2206508021563944,"score_spread":0.2135450451560193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}