{"id":"W2580443921","doi":"10.1182/blood.v124.21.4027.4027","title":"Oxidative Stress and Increased Destruction of Red Blood Cells Contribute to the Pathophysiology of Anemia Caused By DMT1 Deficiency","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Oxidative stress; DMT1; Biology; Erythropoiesis; Red blood cell; Reactive oxygen species; GATA1; Erythroblast; Apoptosis; Anemia; Cell biology; Molecular biology; Haematopoiesis; Immunology; Internal medicine; Biochemistry; Stem cell; Transporter; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804654,0.0001329423,0.000398529,0.00006641941,0.00005690257,0.000002743548,0.00007704819,0.0001232045,0.00003439959],"category_scores_gemma":[0.0002406193,0.00009334597,0.000053645,0.0001863196,0.0001617065,0.00002414073,0.00004207508,0.0001254823,0.000004238737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005927172,"about_ca_system_score_gemma":0.00004375444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001202455,"about_ca_topic_score_gemma":0.00001655853,"domain_scores_codex":[0.9989324,0.0002108727,0.0002983322,0.0002496971,0.0001265117,0.0001821863],"domain_scores_gemma":[0.9989956,0.0002152196,0.0002025056,0.0003068224,0.0001803315,0.0000995291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002308401,0.0004082187,0.004049142,0.0001143311,0.00004740172,0.000002391699,0.0001764525,0.00000518209,0.994114,0.0000895851,0.0003554542,0.0004070166],"study_design_scores_gemma":[0.004781548,0.002355397,0.05522195,0.00006798757,0.0004187189,0.00001693452,0.0001625475,0.00002526878,0.9364558,0.0001797783,0.0002109332,0.0001031161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986337,0.0002000596,0.0001935964,0.0001916598,0.0001136893,0.0003443671,0.0001349072,0.00001982269,0.0001681301],"genre_scores_gemma":[0.9989779,0.00009644709,0.0003683767,0.0003340687,0.00008129987,0.00001549995,0.00007317519,0.00001120456,0.00004200363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05765817,"threshold_uncertainty_score":0.3806539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007105757000375106,"score_gpt":0.2206508021563944,"score_spread":0.2135450451560193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}