{"id":"W2580686727","doi":"10.1172/jci.insight.89574","title":"Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institutes of Health; National Institute of General Medical Sciences; Ragon Institute of MGH, MIT and Harvard; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"CXCR5; Viremia; Antibody; CXCR3; Immunology; Population; T cell; Neutralizing antibody; Biology; Immune system; Virology; B cell; Germinal center; Medicine; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001785956,0.0001752996,0.0002048234,0.0004971834,0.0001989838,0.0003572047,0.0001080809,0.0002848493,0.002177893],"category_scores_gemma":[0.0003310949,0.0001599627,0.00009137185,0.0001268835,0.0001994775,0.000293569,0.0002344477,0.0003984257,0.0002420777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407969,"about_ca_system_score_gemma":0.0001287435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004955336,"about_ca_topic_score_gemma":0.0004450111,"domain_scores_codex":[0.9998761,0.00001849815,0.00001096309,0.00002929222,0.00002376028,0.0000414165],"domain_scores_gemma":[0.9998451,0.00003843572,0.00003644681,0.00001335851,0.00001389786,0.00005258592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009269042,0.0001857656,0.03394908,0.00004346909,0.00001224054,0.0009112977,0.0001713234,0.0001567327,0.9506846,0.0003994218,0.0001935305,0.01236558],"study_design_scores_gemma":[0.0004610379,0.005324106,0.6028,0.00007562267,0.000147798,0.02295041,0.0007126448,0.009820445,0.3496613,0.001546983,0.006440061,0.00005967556],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983058,0.00035556,0.0003449394,0.00001962742,0.000004349559,0.00002119334,0.00006526108,0.0000227181,0.000860443],"genre_scores_gemma":[0.9988555,0.00007188264,0.0003782976,0.0000470076,0.00001510301,0.00001322783,0.0001309487,0.000006665341,0.0004813165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002177893,"threshold_uncertainty_score":0.007285774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02000424020549768,"score_gpt":0.2833888079631711,"score_spread":0.2633845677576734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}