{"id":"W2580891776","doi":"10.1016/j.biochi.2017.01.006","title":"Loss of UCP2 impairs cold-induced non-shivering thermogenesis by promoting a shift toward glucose utilization in brown adipose tissue","year":2017,"lang":"en","type":"article","venue":"Biochimie","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke; Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Thermogenesis; Brown adipose tissue; Uncoupling protein; Thermogenin; Glycolysis; Internal medicine; Endocrinology; Biology; Adipose tissue; White adipose tissue; Fatty acid; Biochemistry; Chemistry; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003958084,0.000229514,0.000477119,0.0001354418,0.0001369796,0.00003332902,0.0002738535,0.0001854782,0.0000788768],"category_scores_gemma":[0.0002625028,0.0002121261,0.00008816981,0.0001309468,0.000083577,0.0001794932,0.000120943,0.0001494083,0.00002726755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000483986,"about_ca_system_score_gemma":0.0001237531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006449083,"about_ca_topic_score_gemma":0.00006099931,"domain_scores_codex":[0.9985261,0.0000572004,0.000421688,0.0003688501,0.0002636874,0.0003625058],"domain_scores_gemma":[0.9987515,0.00003213526,0.0003231465,0.000636954,0.00007015961,0.0001860701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001380539,0.0002844836,0.02963385,0.0003308315,0.00007526764,0.00007387889,0.002698601,6.551502e-7,0.9339597,0.00009853244,0.0001434153,0.03256272],"study_design_scores_gemma":[0.001532996,0.0001998966,0.2755661,0.0002784816,0.0001291415,0.00001164711,0.00006820146,0.0001217178,0.7209905,0.00002229361,0.000905404,0.0001736139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953542,0.001886082,0.0001674752,0.0004211671,0.0001995748,0.0007684422,0.00002728467,0.00004635123,0.001129368],"genre_scores_gemma":[0.9987056,0.0002527402,0.0002988042,0.000070538,0.0001764534,0.0000297357,0.00002398748,0.00004892593,0.0003932501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2459323,"threshold_uncertainty_score":0.8650253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03928886967766856,"score_gpt":0.3060593679066605,"score_spread":0.2667704982289919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}