{"id":"W2580985654","doi":"","title":"The Hedgehog signalling pathway and its role in cancer","year":2001,"lang":"en","type":"dissertation","venue":"Figshare","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"British Medical Association; University Hospitals of Leicester NHS Trust; McMaster University","keywords":"Hedgehog signaling pathway; Hedgehog; Signalling; Cancer; Smoothened; Signalling pathways; Biology; Cancer research; Computational biology; Cell biology; Signal transduction; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002295467,0.0001649374,0.0001999284,0.0005521396,0.0001978612,0.0005006691,0.0001800661,0.0003876522,0.0007158939],"category_scores_gemma":[0.0001990891,0.00009794629,0.0001042866,0.0005751958,0.0004269769,0.0003030872,0.0003507507,0.0003308207,0.0002205792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004851708,"about_ca_system_score_gemma":0.0003385776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001742105,"about_ca_topic_score_gemma":0.001313851,"domain_scores_codex":[0.9998668,0.00003588918,0.0000120448,0.00002020733,0.00003754882,0.00002748233],"domain_scores_gemma":[0.9999367,0.00001403061,0.00001405087,0.000004269271,0.00001501156,0.00001590665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001145489,0.0001704459,0.01816139,0.00311287,0.0001535237,0.003329307,0.0005476075,0.00201489,0.1763076,0.02957183,0.006752523,0.7587326],"study_design_scores_gemma":[0.00009464227,0.001680995,0.3032732,0.001262191,0.0002926083,0.02379288,0.001466807,0.004980384,0.09838062,0.04670737,0.5179356,0.0001325664],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1093275,0.8756573,0.001741586,0.001864897,0.0002011881,0.00002220279,0.0001243779,0.00004574425,0.01101502],"genre_scores_gemma":[0.6407226,0.3503763,0.001626001,0.000555101,0.0002663139,0.00001981779,0.0001455143,0.000005136915,0.006283212],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001742105,"threshold_uncertainty_score":0.003520131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0275764295596425,"score_gpt":0.286447665740937,"score_spread":0.2588712361812945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}