{"id":"W2581018647","doi":"10.1182/blood.v110.11.4898.4898","title":"IFN-g-Stimulated Mesenchymal Stromal Cells Acquire the Ability To Cross-Present Exogenous Soluble Antigens and Lead to an Effective Immune Response.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Antigen processing; Antigen presentation; MHC class I; Antigen; Cytotoxic T cell; Biology; CD8; Antigen-presenting cell; Immune system; Immunology; Major histocompatibility complex; Cross-presentation; T cell; MHC restriction; MHC class II; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355598,0.0004921905,0.0003483264,0.000272848,0.00009608528,0.0002233672,0.0001204046,0.0003548404,0.002050923],"category_scores_gemma":[0.00007137823,0.0001089956,0.0003104199,0.0001654558,0.000177339,0.0001716584,0.0001599238,0.00101157,0.0006508856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000237419,"about_ca_system_score_gemma":0.0001750405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003171657,"about_ca_topic_score_gemma":0.0005292892,"domain_scores_codex":[0.9998088,0.00003722661,0.00002795151,0.00003067748,0.00004599433,0.00004925224],"domain_scores_gemma":[0.9998916,0.00002461483,0.00002277914,0.00001738602,0.00001186803,0.00003162811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001571236,0.00007286018,0.00008995117,0.00002974337,0.000004602652,0.00004479214,0.000008703019,0.0000409903,0.9985531,0.00005507732,0.00004669726,0.0008962959],"study_design_scores_gemma":[0.00002784044,0.0004296755,0.002085923,0.000005058515,0.0000112735,0.000103739,0.00001577088,0.000429745,0.9954304,0.00003551293,0.001423166,0.000001976774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902838,0.00182593,0.003347654,0.0001857078,0.0002341567,0.00006948086,0.001103236,0.0001208763,0.002829051],"genre_scores_gemma":[0.9901478,0.00073103,0.002691907,0.0001475422,0.00003825377,0.00007263583,0.001029417,0.00002643509,0.005115001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002050923,"threshold_uncertainty_score":0.006861091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083513074972603,"score_gpt":0.2806432877075073,"score_spread":0.2698081569577813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}