{"id":"W2581371100","doi":"10.7555/jbr.31.20160096","title":"Insensitivity of PI3K/Akt/GSK3 signaling in peripheral blood mononuclear cells of age-related macular degeneration patients","year":2017,"lang":"en","type":"article","venue":"Journal of Biomedical Research","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Center for Complementary and Alternative Medicine; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Protein kinase B; Peripheral blood mononuclear cell; GSK-3; PI3K/AKT/mTOR pathway; Phosphorylation; Cancer research; Chemistry; GSK3B; Signal transduction; Endocrinology; Internal medicine; Medicine; Biology; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468083,0.000320352,0.0003667365,0.0007733543,0.0003679093,0.0004233971,0.0001010702,0.0003275528,0.001276214],"category_scores_gemma":[0.0005692868,0.0001909606,0.0001465233,0.0004946617,0.0001405028,0.0001590802,0.0002018567,0.0002544641,0.0002939813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001563144,"about_ca_system_score_gemma":0.0001000682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007201768,"about_ca_topic_score_gemma":0.000597834,"domain_scores_codex":[0.9997959,0.00003147326,0.00002605657,0.00007657165,0.00004077832,0.00002928325],"domain_scores_gemma":[0.9998044,0.00002837342,0.00006863754,0.00001446243,0.00003209977,0.00005207346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006594046,0.0003765071,0.7292258,0.0002431258,0.0001662938,0.01111233,0.001065372,0.0001618119,0.2111385,0.0001814948,0.0006472561,0.03908753],"study_design_scores_gemma":[0.0001202636,0.0008470002,0.9715711,0.00002883539,0.000126554,0.0152872,0.0003244554,0.0003917919,0.008716293,0.0001811815,0.002391611,0.00001381873],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969868,0.001595217,0.0002898878,0.00003753651,0.00001149832,0.00001591248,0.0002075073,0.00001511426,0.0008405087],"genre_scores_gemma":[0.9986732,0.0004192206,0.0002183827,0.00005516148,0.00001517941,0.00002278041,0.0002066646,0.00000395118,0.0003855274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001276214,"threshold_uncertainty_score":0.004269421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05167295710698044,"score_gpt":0.3819508973336965,"score_spread":0.330277940226716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}