{"id":"W2581827757","doi":"10.1182/blood.v116.21.3063.3063","title":"The Combination of Cyclophosphamide-Bortezomib-Dexamethasone (CYBOR-D) Is a Highly Effective and Well Tolerated Regimen that Produces Rapid and Complete Hematological Response In Patients with AL Amyloidosis","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; AL amyloidosis; Bortezomib; Internal medicine; Cyclophosphamide; Gastroenterology; Multiple myeloma; Dexamethasone; Amyloidosis; Regimen; Neutropenia; Surgery; Chemotherapy; Immunology; Immunoglobulin light chain","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003045241,0.0003026339,0.0004743892,0.0002400251,0.0003041226,0.0002487262,0.000200809,0.0002014775,0.00088524],"category_scores_gemma":[0.0004454094,0.0001512518,0.0002389216,0.000179134,0.0002308492,0.0001493138,0.0001557893,0.000462048,0.0002789119],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002327463,"about_ca_system_score_gemma":0.0002488445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002868998,"about_ca_topic_score_gemma":0.0009343369,"domain_scores_codex":[0.9998092,0.0000713936,0.0000219867,0.00002775983,0.00003363995,0.0000361454],"domain_scores_gemma":[0.9997945,0.000067041,0.00003310343,0.00001565404,0.00001034929,0.0000792327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.05008316,0.009448637,0.3928302,0.0005631077,0.0005783592,0.008771851,0.0005798382,0.002181412,0.1931914,0.0002362174,0.004430372,0.3371054],"study_design_scores_gemma":[0.01662933,0.211983,0.6619172,0.0001062895,0.0004951748,0.04204284,0.0002624737,0.004432898,0.04714272,0.0002310168,0.01469881,0.0000582862],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966551,0.001612018,0.0004361845,0.00007209647,0.00001497706,0.00008730573,0.00007207358,0.00003067574,0.001019542],"genre_scores_gemma":[0.9986355,0.0003975221,0.000457801,0.00007662602,0.00003357576,0.00003806472,0.0001624746,0.0000032444,0.0001952349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00088524,"threshold_uncertainty_score":0.002961457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005340306155243384,"score_gpt":0.2197950604385724,"score_spread":0.214454754283329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}