{"id":"W2582171842","doi":"10.1182/blood.v126.23.737.737","title":"Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome with Multi-Organ Dysfunction: Final Results from a Pivotal, Historically Controlled, Phase 3 Trial","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Defibrotide; Hepatic veno-occlusive disease; Medicine; Internal medicine; Ascites; Creatinine; Organ dysfunction; Gastroenterology; Dialysis; Hematopoietic stem cell transplantation; Hepatorenal syndrome; Transplantation; Surgery; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004146728,0.001097897,0.001906079,0.0003192906,0.0003710703,0.001371277,0.0006482086,0.001472582,0.00272427],"category_scores_gemma":[0.001431525,0.0002762943,0.00200136,0.0003273433,0.0007693747,0.0008738963,0.00028638,0.002342761,0.0005510737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005546876,"about_ca_system_score_gemma":0.0009534523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003552049,"about_ca_topic_score_gemma":0.001286558,"domain_scores_codex":[0.9992465,0.0003980017,0.00004656846,0.00009606817,0.0000785044,0.0001344024],"domain_scores_gemma":[0.9985662,0.000351619,0.0003413157,0.0001029405,0.0001213853,0.0005165295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8430812,0.01756334,0.007304359,0.001582571,0.003560358,0.0004362422,0.0003139996,0.001299458,0.02523287,0.0005998209,0.007491042,0.09153464],"study_design_scores_gemma":[0.816925,0.1620445,0.01285724,0.0001286328,0.001313565,0.0004126011,0.00005995315,0.0007279888,0.001673206,0.0005167632,0.003304557,0.00003603793],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737346,0.01436943,0.0009641429,0.002021429,0.0004311706,0.002726821,0.002067796,0.0001006865,0.003583953],"genre_scores_gemma":[0.9823544,0.004709204,0.002452636,0.003140601,0.0005042845,0.002413045,0.002491141,0.00002475796,0.001910034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004146728,"threshold_uncertainty_score":0.02193022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04923349367987831,"score_gpt":0.2836615923189189,"score_spread":0.2344280986390405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}