{"id":"W2582289152","doi":"10.1182/blood.v126.23.177.177","title":"Disruption of Direct 3-Dimensional (3D) Telomere-TRF2 (Telomere Related Factor 2) Interaction Is a Hallmark of Primary Hodgkin (H) and Reed-Sternberg (RS) Cells","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; McGill University; Jewish General Hospital","funders":"","keywords":"Telomere; Biology; Germinal center; Molecular biology; Pathology; Immunology; Genetics; B cell; Antibody; Medicine; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001930138,0.0002732351,0.0001624231,0.0002517128,0.0002316535,0.0003219552,0.0002639176,0.0002821217,0.002297992],"category_scores_gemma":[0.000107002,0.0002195164,0.0002980122,0.0001406643,0.0003350961,0.0001533785,0.0003025404,0.0004039412,0.0007785944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003167819,"about_ca_system_score_gemma":0.0002075705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007173137,"about_ca_topic_score_gemma":0.001832751,"domain_scores_codex":[0.9997973,0.00001643946,0.00001515295,0.00006218298,0.00007501114,0.00003398538],"domain_scores_gemma":[0.9998696,0.00002684373,0.00003837691,0.00002822968,0.00001446208,0.00002257856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001641104,0.000005352206,0.0002121893,0.000017361,0.00000315082,0.00003948625,0.0000109297,0.00004423266,0.9989923,0.00006679379,0.00003654571,0.0005553092],"study_design_scores_gemma":[0.000008618751,0.0001088487,0.009596962,0.000004086025,0.00001133385,0.0006108343,0.00003691482,0.0008939466,0.9847718,0.00004923766,0.003901336,0.000006109127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517248,0.001115578,0.0408005,0.0001601335,0.00005409943,0.0001010939,0.001451917,0.0004977579,0.004094117],"genre_scores_gemma":[0.970993,0.0004676982,0.02146537,0.00009295379,0.000009547814,0.0001400846,0.001529173,0.0000879593,0.005214106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002297992,"threshold_uncertainty_score":0.007687569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02556398286729912,"score_gpt":0.2589512014879832,"score_spread":0.233387218620684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}