{"id":"W2582665266","doi":"10.3390/toxins9020049","title":"Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection in the Neonatal Gnotobiotic Piglet Model","year":2017,"lang":"en","type":"article","venue":"Toxins","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"Centers for Disease Control and Prevention","keywords":"Microbiology; Escherichia coli; Shiga toxin; Monoclonal antibody; Diarrhea; Toxin; Antibody; Virology; Diarrheal disease; Diarrheal diseases; Biology; Medicine; Immunology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003726459,0.0004319991,0.0006719512,0.000224959,0.0001234614,0.0001951604,0.0003442567,0.0004740479,0.0007299421],"category_scores_gemma":[0.0001733171,0.0001603286,0.0003933901,0.00007894079,0.0003200751,0.0002637393,0.0001250686,0.0007107513,0.0001718805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611664,"about_ca_system_score_gemma":0.0002423989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004392454,"about_ca_topic_score_gemma":0.0006940637,"domain_scores_codex":[0.9998732,0.0000300214,0.00001352786,0.00002497164,0.00002174814,0.00003663379],"domain_scores_gemma":[0.9998448,0.00002710858,0.00004019738,0.0000141317,0.000011548,0.00006227679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009886708,0.004670545,0.0007409464,0.0002073049,0.00006287044,0.0001400493,0.00006425179,0.0002682791,0.9727051,0.00005856259,0.0001668136,0.01102854],"study_design_scores_gemma":[0.002405728,0.2527569,0.030191,0.00005380397,0.0002457022,0.0006831998,0.00008396535,0.001900231,0.7099526,0.00006089456,0.001633882,0.0000321895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987627,0.0007166861,0.0001277086,0.00003682854,0.00002983846,0.00002525084,0.00005602571,0.00001833737,0.0002266064],"genre_scores_gemma":[0.9975041,0.0009791928,0.0004038038,0.00005889332,0.00003197345,0.00005350192,0.0002193595,0.00000375011,0.0007454955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007299421,"threshold_uncertainty_score":0.002441943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02987940046526246,"score_gpt":0.3171236473288019,"score_spread":0.2872442468635394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}